Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
NOT_YET_RECRUITING
130 participants
OBSERVATIONAL
2025-09-01
2026-12-30
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Association Between Peri-procedural Myocardial Injury and Quantitative Blood Flow Ratio
NCT07110298
Relation Between Lymphocyte-to-C-Reactive Protein Ratio and Coronary Artery Disease Complexity
NCT06958562
Association of Triglyceride-glucose Index With Cardiac Hemodynamics
NCT05702112
The Association Between Central Aortic Blood Pressure Indices and Severity of Coronary Artery Disease
NCT02471768
Triglyceride-Glucose Indices and Left Ventricular Speckle Tracking in Predicting Coronary Artery Disease Severity
NCT07063628
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Recent studies have highlighted the significance of novel lipid-derived markers, particularly the triglyceride-glucose (TyG) index and the triglyceride-to-high-density lipoprotein cholesterol (TG/HDL-C) ratio, as potential predictors of insulin resistance, subclinical atherosclerosis, and cardiovascular events【1,3】. The TyG index and TG/HDL-C ratio are simple, cost-effective markers derived from routine laboratory parameters and have shown promising associations with metabolic syndrome, endothelial dysfunction, and coronary artery disease (CAD) severity【3,4】.
Despite emerging evidence in older adults, limited data exist regarding the utility of these markers in predicting ACS among the young population, where conventional risk scores often underestimate risk【4,5】. Early detection through these markers could improve risk stratification and guide preventive strategies.
This study aims to evaluate the significance of the TyG index and TG/HDL-C ratio as predictors of ACS in young adults, providing insight into their potential role in primary prevention
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
COHORT
CROSS_SECTIONAL
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
PCI
Coronary angiography then SYNTAX score calculation
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
Age 18-40 years. Confirmed diagnosis of ACS (STEMI, NSTEMI). Willingness to participate with informed consent.
Exclusion Criteria
18 Years
40 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Assiut University
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Saleh Mohamed Saleh
Principal Investigator
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Khaled Mohamed Abdallah, Professor
Role: STUDY_DIRECTOR
Assuit university - faculty of medicine
Central Contacts
Reach out to these primary contacts for questions about participation or study logistics.
Mohamed Osman Abdelhameed, Lecturer
Role: CONTACT
References
Explore related publications, articles, or registry entries linked to this study.
Kim MK, Ahn CW, Kang S, Nam JS, Kim KR, Park JS. Relationship between the triglyceride glucose index and coronary artery calcification in Korean adults. Cardiovasc Diabetol. 2017 Aug 23;16(1):108. doi: 10.1186/s12933-017-0589-4.
Khalaji A, Behnoush AH, Pasebani Y, Rafati A, Mahmoodi T, Arzhangzadeh A, Shamshiri Khamene S, MohammadKhawajah I, Mehrani M, Vasheghani-Farahani A, Masoudkabir F, Najafi K, Askari MK, Harrison A, Nelson JR, Hosseini K, Hernandez AV. Triglyceride-glucose index as a predictor of cardiac adverse events in acute coronary syndrome patients undergoing percutaneous coronary intervention: role of diabetes. BMC Cardiovasc Disord. 2024 Sep 27;24(1):514. doi: 10.1186/s12872-024-04191-5.
Liu Y, Zhu B, Zhou W, Du Y, Qi D, Wang C, Cheng Q, Zhang Y, Wang S, Gao C. Triglyceride-glucose index as a marker of adverse cardiovascular prognosis in patients with coronary heart disease and hypertension. Cardiovasc Diabetol. 2023 Jun 9;22(1):133. doi: 10.1186/s12933-023-01866-9.
Ren X, Chen ZA, Zheng S, Han T, Li Y, Liu W, Hu Y. Association between Triglyceride to HDL-C Ratio (TG/HDL-C) and Insulin Resistance in Chinese Patients with Newly Diagnosed Type 2 Diabetes Mellitus. PLoS One. 2016 Apr 26;11(4):e0154345. doi: 10.1371/journal.pone.0154345. eCollection 2016.
da Silva A, Caldas APS, Hermsdorff HHM, Bersch-Ferreira AC, Torreglosa CR, Weber B, Bressan J. Triglyceride-glucose index is associated with symptomatic coronary artery disease in patients in secondary care. Cardiovasc Diabetol. 2019 Jul 11;18(1):89. doi: 10.1186/s12933-019-0893-2.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
Predictors for ACS
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.