Peristeen Light Explorative Clinical Investigation

NCT ID: NCT07126327

Last Updated: 2025-09-04

Basic Information

• Recruitment Status: NOT_YET_RECRUITING
• Clinical Phase: NA
• Total Enrollment: 60 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2025-11-01
• Study Completion Date: 2026-08-01

Brief Summary

The goal of this exploratory clinical investigation is to understand the clinical benefits of Peristeen Light in adult patients with faecal incontinence, chronic constipation and/or time-consuming bowel management procedures.

The primary objective is to evaluate changes in bowel-function when using Peristeen Light. Participants will use Peristeen Light for 12 weeks test period.

Detailed Description

The goal of this exploratory clinical investigation is to understand the clinical benefits of Peristeen Light in adult patients with faecal incontinence, chronic constipation and/or time-consuming bowel management procedures.

The primary endpoint is bowel function measured on a 10 cm Visual Analog Scale (VAS) at Baseline Visit and end of Clinical Investigation visit.

Participants will use Peristeen Light for 12 weeks test period.

Conditions

Faecal Incontinence; Constipation - Functional

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

Exploratory single-arm interventional investigation

Prescription of Peristeen Light transanal irrigation system at enrolment to use for a 12 week test period

Group Type: EXPERIMENTAL

Peristeen Light - trans anal irrigation system

Intervention Type: DEVICE

Subjects naive to TAI will use Peristeen Light trans anal irrigation

Interventions

Peristeen Light - trans anal irrigation system

Subjects naive to TAI will use Peristeen Light trans anal irrigation

Intervention Type: DEVICE

Eligibility Criteria

Inclusion Criteria

• Has given written informed consent
• Is at least 18 years old
• Has full legal capacity
• Is able (assessed by investigator) and willing to adhere to clinical investigational procedures during clinical investigation-al duration
• Has access to and is able to use a smartphone
• Has constipation and/or faecal incontinence based on one or more of the following symptoms during the last 3 month: Straining in more than 25% of defecations, lumpy stools (Bristol Stool Type 1 and 2) in more than 25% of defecations, sensation of incomplete evacuation in more than 25% of defecations, sensation of anorectal obstruction/blockage in more than 25% of defecations, need to use manual maneuvers to facilitate defecation in more than 25% of defecations, fewer than three spontaneous bowel movements per week, loose stools are rarely present without use of laxatives, recurrent uncontrolled passage of faecal material (other words to describe this could be: Soiling, leak-age, passive faecal incontinence of flatus, mucus and/or stool)
• Is assessed (by investigator) to have a need for low-volume TAI minimum every other day

Exclusion Criteria

• Is participating in any other clinical investigation during this investigation
• Has previously completed this investigation
• Is former or current user of transanal irrigation (low- and high volume)
• Has known hypersensitivity towards the device used in the investigation
• Is pregnant
• Has known anal stenosis
• Has active/recurrent colorectal cancer
• Has had anastomotic colorectal surgery within the last 3 months
• Has ischaemic colitis
• Has active inflammatory bowel disease
• Has acute diverticulitis or diverticular abscess
• Has medicine induced constipation (e.g. due to opioids)
• Has chronic diarrhea
• Has bowel dysfunction due to neurogenic disorder(s)
• Is in need of high-volume TAI (as estimated by investigator)

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Coloplast A/S

INDUSTRY

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Other Identifiers

CP378

Identifier Type: -

Identifier Source: org_study_id