Comparison Between Coolprep and Picolyte for Bowel Cleansing

NCT ID: NCT01774175

Last Updated: 2013-01-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

250 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-01-31

Study Completion Date

2014-03-31

Brief Summary

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The investigators will compare with PEG+ascorbic acid and picosulfate+magnesium citrate about bowel preparation, patient's satisfaction, side effects to identify effectiveness of new bowel preparation drug.

Detailed Description

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The investigators can find easily colon cancer and poly by colonoscopy, but bowel preparation is very important to find the lesion. Desirable bowel preparation drug must be clearly removed stool, effective on colonoscopic finding and pathologic finding, quickly administrated agent and eliminated stool, comfort for patient, and less side effects.

PEG is very safe osmotic laxative. New agent(coolprep) which add ascorbic acid is less salty and less volume. Picosulfate+magnesium citrate(picolyte) taste orange, can be easily prepared bowel for colonoscopy by good taste and small volume. Magnesium with citrate acts like osmotic agent, picosulfate acts irritant agent.

The investigators will compare with PEG+ascorbic acid and picosulfate+magnesium citrate about bowel preparation, patient's satisfaction, side effects to identify effectiveness of new bowel preparation drug.

Conditions

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Stasis; Colon

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Coolprep

A total of 2L A : NaCl 5.382g KCl 2.03g Sodium sulfate 15g Polyethylene glycol 3350 200.0g B : Ascorbic acid 9.4g Sodium ascorbate 11.8g

No interventions assigned to this group

Picolyte

Sodium picosulfate 30.0mg Magnesium citrate 10.5g + 36.0g

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Age : over 19 years
* Who will be done colonoscopy
* Who accepted informed consent

Exclusion Criteria

* Age : over 80 years
* Electrolyte imbalance
* Liver function test abnormality, ascites(over 2 times, \>Child class B)
* ARF or CRF(GFS\<30)
* Recent MI(\< 6months) or Unstable angina pectoris
* Congestive heart failure(NYHA \> 2)
* Inflammatory bowel disease
* Abdominal minor surgery
Minimum Eligible Age

19 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Gachon University Gil Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Chung Jun Won

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Jun Won Chung, Professor

Role: STUDY_DIRECTOR

Gachon University Gil Medical School

Other Identifiers

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COOLPREPICOLYTE

Identifier Type: -

Identifier Source: org_study_id

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