Optimization of Oocyte Warming Protocols

NCT ID: NCT07105891

Last Updated: 2025-10-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

399 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-09-16

Study Completion Date

2025-10-30

Brief Summary

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This is a retrospective study with a sibling design comparing new oocyte thawing protocols (rapid and ultra-rapid) with the traditional method

Detailed Description

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Conditions

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Oocyte Cryopreservation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

sibling design
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Standard

Standard thawing

Group Type OTHER

Thawing protocol

Intervention Type OTHER

Standard thwaing

Fast

Fast thawing

Group Type OTHER

thawing protocol

Intervention Type OTHER

Fast thawing

Ultrafast

Ultrafast thawing

Group Type OTHER

thawing protocol

Intervention Type OTHER

Ultrafast thawing

Interventions

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Thawing protocol

Standard thwaing

Intervention Type OTHER

thawing protocol

Fast thawing

Intervention Type OTHER

thawing protocol

Ultrafast thawing

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Vitrified oocytes from the Centro Scienze della Natalità, IRCCS San Raffaele Hospital
* Patients who explicitly consented to the disposal of their stored gametes and authorized their use for research purposes through the informed consent process
* Oocytes cryopreserved using the vitrification technique
* Patients age 20-39 yo

Exclusion Criteria

* All oocytes cryopreserved using the slow freezing technique
* Oocytes from patients older than 40 years
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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IRCCS San Raffaele

OTHER

Sponsor Role lead

Responsible Party

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Enrico Papaleo

MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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IRCCS San Raffaele Hospital

Milan, Lombardy, Italy

Site Status

Countries

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Italy

Other Identifiers

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OVOfast

Identifier Type: -

Identifier Source: org_study_id

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