Clinical Characteristics and Prognosis of Simultaneous Versus Delayed Resection for Synchronous Colorectal Liver Metastasis: A Nationwide Multicenter Study Utilizing Propensity Score Matching Analysis

NCT ID: NCT07082335

Last Updated: 2026-01-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

679 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-01-01

Study Completion Date

2024-01-01

Brief Summary

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Colorectal cancer (CRC) often metastasizes to the liver, with synchronous metastases observed in 20% of cases. Surgical resection is the primary treatment, but the impact of simultaneous and staged resections on clinical outcomes remains unclear. This study employs propensity score matching (PSM) in a nationwide survey to compare clinical characteristics, complications, and survival, providing valuable insights for optimizing the management of colorectal liver metastases.

Detailed Description

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Conditions

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Colorectal Cancer (CRC)

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

1\) a histologically confirmed diagnosis of colorectal cancer with liver metastases; and 2) age ≥ 18 years

Exclusion Criteria

1\) extrahepatic metastases; and 2) ineligibility for curative surgical resection based on preoperative assessment.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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RenJi Hospital

OTHER

Sponsor Role collaborator

Shanghai 10th People's Hospital

OTHER

Sponsor Role lead

Responsible Party

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Zhang Feng-Min

MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Shanghai Tenth People Hospital, Yanchang Road, Jingan District, Shanghai,

Shanghai, Jingan, China

Site Status

Countries

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China

Other Identifiers

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25K10

Identifier Type: -

Identifier Source: org_study_id

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