the Effect of Adult Intubated Patient Clinical Pathway on Post-extubation Complications Prevention

NCT ID: NCT07081399

Last Updated: 2025-07-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

EARLY_PHASE1

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-08-08

Study Completion Date

2025-08-31

Brief Summary

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Post- extubation complications delay the complete recovery of critically ill patient. The clinical pathway is one strategies that help to manage and control these complications.

Detailed Description

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The presence of endotracheal tube is associated with various fatal complications which are diagnosed mainly in post- extubation time. Those complications include laryngeal edema, laryngospasm, and post-extubation dysphagia which delay the complete recovery of critically ill patient. The clinical pathway is one of the excellent strategies that help the critical care staff to manage and control these complications

Conditions

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Dysphagia Dysphagia Rehabilitation

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

non- clinical pathway group and clinical pathway group
Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors
post-extubation complications outcomes (laryngospasm, laryngeal edema and dysphagia)

Study Groups

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non-clinical pathway group

non-clinical pathway group who received the routine hospital care.

Group Type NO_INTERVENTION

No interventions assigned to this group

clinical pathway group

the clinical pathway group who recieved the CP interventions such as: ETTcuff pressure measurement, ETT suctioning, measures to prevent laryngeal edema, swallowing rehabilitation, maneuvers to prevent laryngospasm

Group Type EXPERIMENTAL

No interventions assigned to this group

Interventions

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ETT cuff pressure monitoring, ETT suctioning, cough augmentation technique, swallowing exercises,: Nebulized budesonide 1mg and IV methylprednisolone 40 mg we

cough augmentation, larson maneuver, swallowing rehabilitation

Intervention Type COMBINATION_PRODUCT

Eligibility Criteria

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Inclusion Criteria

* Adult (\>18 years)
* orally intubated patients for the first time attached with MV for less than two weeks
* with Glasgow coma scale (GCS) from 13-15.

Exclusion Criteria

* patients admitted with high risk for laryngeal edema,
* difficult intubation,
* ETT/anterior-posterior diameter ˃45%,
* self-extubation, and
* planned for tracheostomy.
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Damanhour University

OTHER

Sponsor Role lead

Responsible Party

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[email protected]

assistant lecturer critical care and emergency nursing

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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sahar youness effect of adult intubated CP on post-extubation complications

Role: STUDY_CHAIR

Locations

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Faculty of Nursing, Damanhour University

Damanhūr, Egypt, Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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heba attia effect of adult intubated CP on post-extubation complications

Role: CONTACT

045 01274855242

Facility Contacts

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effect of adult intubated CP on post-extubation complications

Role: primary

045 3311679

effect of adult intubated CP on post-extubation complications

Role: backup

Other Identifiers

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1a2b3c4d5e6f7g8h9i10j11k12l13m

Identifier Type: -

Identifier Source: org_study_id

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