Penile Skin Versus Buccal Mucosal Graft in Augmentation Urethroplasty for Long Anterior Urethral Stricture
NCT ID: NCT07074717
Last Updated: 2025-07-20
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
80 participants
INTERVENTIONAL
2025-01-01
2025-12-01
Brief Summary
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Detailed Description
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In 1993, McAninch described a circular fasciocutaneous flap for the management of penile urethral stricture up to 15 cm that showed excellent cosmetic and functional outcomes due to this being a hairless, flexible flap with a rich vascular supply.
Buccal mucosal graft (BMG) was rediscovered and popularized in 1992 by Burger et al., then El-Kassaby et al. in 1993 published a series using buccal mucosal graft to repair anterior urethral stricture. Buccal mucosal graft became an ideal urethral substitute due to easy harvesting, hairlessness and compatibility in a wet environment.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Buccal Mucosal Graft (BMG)
Participants will undergo dorsal onlay augmentation urethroplasty using a buccal mucosal graft harvested from the inner cheek. The procedure is performed under spinal or general anesthesia. Graft is sutured dorsally over the strictured urethral segment after excision of the fibrotic tissue.
Buccal Mucosal Graft (BMG) Urethroplasty
Urethroplasty using a buccal mucosal graft harvested from the inner cheek. The graft is dorsally onlaid to reconstruct the strictured urethral segment. The procedure is conducted under spinal or general anesthesia.
Penile Skin Graft (PSG)
Participants will undergo dorsal onlay augmentation urethroplasty using a penile skin graft harvested from the ventral surface of the penis. The hairless skin is prepared and sutured dorsally over the strictured urethral segment. The procedure is done under spinal or general anesthesia.
Penile Skin Graft (PSG) Urethroplasty
Urethroplasty using a penile skin graft harvested from the ventral surface of the penis. The graft is applied dorsally after excision of the fibrotic urethral segment. The surgery is performed under spinal or general anesthesia.
Interventions
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Buccal Mucosal Graft (BMG) Urethroplasty
Urethroplasty using a buccal mucosal graft harvested from the inner cheek. The graft is dorsally onlaid to reconstruct the strictured urethral segment. The procedure is conducted under spinal or general anesthesia.
Penile Skin Graft (PSG) Urethroplasty
Urethroplasty using a penile skin graft harvested from the ventral surface of the penis. The graft is applied dorsally after excision of the fibrotic urethral segment. The surgery is performed under spinal or general anesthesia.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Patients with previous failed urethral dilatation or direct vision internal urethrotomy (DVIU)
Exclusion Criteria
* Patients with history of hypospadias repair
* Patients with recurrent urethral stricture after failed previous urethroplasty
18 Months
MALE
No
Sponsors
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Tanta University
OTHER
Responsible Party
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Mohamed Ibrahim Ahmed Elmaadawy
Lecturer of Urology, Faculty of Medicine, Tanta University, Tanta, Egypt.
Locations
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Tanta University
Tanta, El-Gharbia Governorate, Egypt, Egypt
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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36264PR1074/1/25
Identifier Type: -
Identifier Source: org_study_id
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