Combined Amniotic Membrane and Platelet Rich Plasma Clot for Management of Central Corneal Perforation
NCT ID: NCT03500796
Last Updated: 2021-05-19
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
10 participants
INTERVENTIONAL
2018-04-15
2020-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
TREATMENT
NONE
Study Groups
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Corneal perforation patients
Patients who had/impeding corneal perforation due to melting of the cornea after infection with a corneal pathogen (bacterial or viral), with no previous surgical intervention.
Patients will undergo:
Platelet rich plasma clot implantation Wound closure with amniotic membrane
Platelet rich plasma clot implantation
Implantation of a platelet rich plasma clot, which is created from the plasma of the patients, and refrigerated to be inserted under the sealing amniotic membrane
Wound closure with amniotic membrane
Closure of the corneal perforation with a synthetic amniotic membrane with a 2 mm safety margin
Interventions
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Platelet rich plasma clot implantation
Implantation of a platelet rich plasma clot, which is created from the plasma of the patients, and refrigerated to be inserted under the sealing amniotic membrane
Wound closure with amniotic membrane
Closure of the corneal perforation with a synthetic amniotic membrane with a 2 mm safety margin
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* posterior segment pathology
* non seeing eye
ALL
No
Sponsors
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Minia University
OTHER
Responsible Party
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Ahemd Abdelghany
Lecturer of Ophthalmology, Faculty of Medicine
Principal Investigators
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Ahmed A Abdelghany, MD
Role: PRINCIPAL_INVESTIGATOR
Assistant professor of Ophthalmology, Faculty of Medicine
Locations
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Faculty of Medicine
Minya, , Egypt
Countries
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Other Identifiers
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56-2/2018
Identifier Type: -
Identifier Source: org_study_id
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