Three Different Cross-linking Protocols for Treatment of Pediatric Keratoconus
NCT ID: NCT05691335
Last Updated: 2023-03-31
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
97 participants
INTERVENTIONAL
2018-06-01
2023-01-05
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Standard CXL
Patients treated according to Dresden Protocol with epithelium-off CXL.
Standard CXL
Epithelium-off CXL performed by removal of corneal epithelium, instillation of riboflavin onto the cornea followed by UVA corneal irradiation for 30 minutes.
Accelerated CXL
Patients treated according to accelerated Protocol with epithelium-off CXL.
Accelerated CXL
Epithelium-off CXL performed by removal of corneal epithelium, instillation of riboflavin onto the cornea followed by UVA corneal irradiation for 5 minutes.
Transepithelial CXL
Patients treated according to transepithelial Protocol with epithelium-on CXL.
Transepithelial CXL
Epithelium-on CXL performed by instillation of riboflavin onto the cornea followed by UVA corneal irradiation for 5 minutes.
Interventions
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Standard CXL
Epithelium-off CXL performed by removal of corneal epithelium, instillation of riboflavin onto the cornea followed by UVA corneal irradiation for 30 minutes.
Accelerated CXL
Epithelium-off CXL performed by removal of corneal epithelium, instillation of riboflavin onto the cornea followed by UVA corneal irradiation for 5 minutes.
Transepithelial CXL
Epithelium-on CXL performed by instillation of riboflavin onto the cornea followed by UVA corneal irradiation for 5 minutes.
Eligibility Criteria
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Inclusion Criteria
* keratoconus stage I-III ABCD keratoconus grading system
Exclusion Criteria
* previous eye surgery
* current eye infection or pathology
12 Years
18 Years
ALL
No
Sponsors
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Sohag University
OTHER
Responsible Party
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Prof. Mohammed Iqbal
Professor
Principal Investigators
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Mohammed Iqbal, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
Sohag University
Locations
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Faculty of medicine
Sohag, , Egypt
Countries
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Other Identifiers
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10-4/2018
Identifier Type: -
Identifier Source: org_study_id
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