Buccal Mucosal Graft for the Repair of Iatrogenic Pelviureteric Junction Obstruction or Ureteric Stricture.

NCT ID: NCT04503330

Last Updated: 2020-08-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-10-01

Study Completion Date

2021-12-01

Brief Summary

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Prospective study to evaluate the safety and efficacy of using buccal mucosal graft for repairing complex cases of iatrogenic pelvi ureteric junction obstruction and long segment ureteric stricture disease.

Detailed Description

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A graft of buccal mucosa will be used to augment either the narrow unhealthy pelviureteric junction or a narrow long segment of the ureter.

after freeing the narrowed part, a posterior incision will be made in the ureter or renal pelvis then the graft will be implanted on the psoas muscle using interrupted sutures in a position the allows easy anastomosis to the ureter or renal pelvis.

Alternatively a lateral incision in the renal pelvis or the ureter may be done for the graft anastomosis and then surrounded with omenal flap to ensure a good blood supply for the graft.

Conditions

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Pelvi Ureteric Junction Obstruction or Ureteral Stricture

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

20 patients with iatrogenic pelviureteric junction obstruction or ureteric stricture disease
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Patients with iatrogenic PUJO

patients with iatrogenic PUJO or long segment ureteric stricture disease for safety and efficacy of using buccal graft for repair

Group Type EXPERIMENTAL

buccal mucosal graft to repair iatrogenic PUJO

Intervention Type PROCEDURE

Augmented buccal mucosal graft anastomosis to repair iatrogenic PUJO or long segment ureteric stricture disease

Interventions

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buccal mucosal graft to repair iatrogenic PUJO

Augmented buccal mucosal graft anastomosis to repair iatrogenic PUJO or long segment ureteric stricture disease

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

\- any patient with iatrogenic pelviureteric junction obstruction or long segment ureteric stricture

Exclusion Criteria

* elderly patients unfit for general anaesthesia.
Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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Ahmed Abozamel

principal investigator urologist

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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cairo univeristy

Identifier Type: -

Identifier Source: org_study_id

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