Effectiveness of AI-Supervised Mobile Exercise Application in Patients With Knee Osteoarthritis

NCT ID: NCT07066514

Last Updated: 2025-07-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-08-31

Study Completion Date

2025-10-31

Brief Summary

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This study aims to evaluate the effectiveness of an artificial intelligence (AI)-supported mobile application that supervises home-based exercise programs in patients with knee osteoarthritis. A total of 80 participants aged 40 to 80 will be randomly assigned to one of two groups: a mobile application exercise group or a home exercise booklet group. Both groups will receive the same standardized stretching, strengthening, and range of motion exercises designed for knee osteoarthritis. The mobile app provides real-time feedback and supervision using the device's camera and artificial intelligence algorithms to track and guide exercise performance.

Participants in the app group will perform exercises with supervision via the app interface, while the control group will follow the same exercises using printed instructions. Both groups will exercise 3 to 4 times per week for 4 weeks. The study will compare pain levels, physical function, and balance before and after the intervention using validated outcome measures such as the WOMAC Index and the Visual Analog Scale.

This study may help determine whether AI-supported digital tools can improve exercise adherence and outcomes in patients with knee osteoarthritis.

Detailed Description

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Conditions

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Knee Osteoarthritis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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AI-Based Mobile Home Exercise Group

Group Type EXPERIMENTAL

AI-Supervised Mobile Exercise Program

Intervention Type BEHAVIORAL

This intervention involves the use of an artificial intelligence (AI)-supported mobile application that delivers a personalized exercise program to patients with knee osteoarthritis. The app supervises exercise execution in real time using the device's camera and AI algorithms to track movements, count repetitions, and assess form accuracy. The program includes stretching, strengthening, and range of motion exercises performed 3-4 times per week for 4 weeks. The app provides instructional videos, personalized feedback, reminders, and records user performance. No video or personal images are stored; only anonymized motion data are collected and securely stored.

Standard Home Exercise Group

Group Type EXPERIMENTAL

Booklet-Guided Home Exercise Program

Intervention Type BEHAVIORAL

This intervention provides patients with a standardized home exercise program in printed booklet format. The program includes the same evidence-based stretching, strengthening, and range of motion exercises used in the mobile application group, performed 3-4 times per week for 4 weeks. Participants receive one-time in-person instruction on proper form but no ongoing supervision or feedback during the program. Adherence and technique are self-monitored.

Interventions

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AI-Supervised Mobile Exercise Program

This intervention involves the use of an artificial intelligence (AI)-supported mobile application that delivers a personalized exercise program to patients with knee osteoarthritis. The app supervises exercise execution in real time using the device's camera and AI algorithms to track movements, count repetitions, and assess form accuracy. The program includes stretching, strengthening, and range of motion exercises performed 3-4 times per week for 4 weeks. The app provides instructional videos, personalized feedback, reminders, and records user performance. No video or personal images are stored; only anonymized motion data are collected and securely stored.

Intervention Type BEHAVIORAL

Booklet-Guided Home Exercise Program

This intervention provides patients with a standardized home exercise program in printed booklet format. The program includes the same evidence-based stretching, strengthening, and range of motion exercises used in the mobile application group, performed 3-4 times per week for 4 weeks. Participants receive one-time in-person instruction on proper form but no ongoing supervision or feedback during the program. Adherence and technique are self-monitored.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Aged between 40 and 80 years
* Diagnosed with knee osteoarthritis according to ACR criteria
* Referred to physical therapy by a physician for knee osteoarthritis
* Able to use a smartphone or tablet
* Having regular access to the internet
* Voluntarily agrees to participate in the study

Exclusion Criteria

* History of knee surgery or currently undergoing surgical treatment
* Received physical therapy or rehabilitation for knee OA within the past 6 months
* Lack of access to a mobile device or internet
* Any neurological, cardiovascular, or musculoskeletal condition that prevents safe participation in exercise
* Cognitive impairment or psychiatric disorder interfering with exercise adherence
* Inability to follow instructions or use the mobile app interface
* Any condition that would contraindicate participation in a home-based exercise program
Minimum Eligible Age

40 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Uludag University

OTHER

Sponsor Role lead

Responsible Party

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Selim Mahmut GÜNAY

Asst Prof

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Bursa Uludag University

Bursa, Nilüfer, Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Central Contacts

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Selim Mahmut GÜNAY, Asst Prof

Role: CONTACT

+90 0224 295 0844

Facility Contacts

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Büşra Şahin, MsC

Role: primary

+90 0224 295 0844

References

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Nelligan RK, Hinman RS, Kasza J, Crofts SJC, Bennell KL. Effects of a Self-directed Web-Based Strengthening Exercise and Physical Activity Program Supported by Automated Text Messages for People With Knee Osteoarthritis: A Randomized Clinical Trial. JAMA Intern Med. 2021 Jun 1;181(6):776-785. doi: 10.1001/jamainternmed.2021.0991.

Reference Type BACKGROUND
PMID: 33843948 (View on PubMed)

Xiang XN, Wang ZZ, Hu J, Zhang JY, Li K, Chen QX, Xu FS, Zhang YW, He HC, He CQ, Zhu SY. Telehealth-Supported Exercise or Physical Activity Programs for Knee Osteoarthritis: Systematic Review and Meta-Analysis. J Med Internet Res. 2024 Aug 2;26:e54876. doi: 10.2196/54876.

Reference Type BACKGROUND
PMID: 39094114 (View on PubMed)

Other Identifiers

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2025-2/19

Identifier Type: -

Identifier Source: org_study_id

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