Electromyographic Assessment of Sleep Bruxism in Patients With Stage III and IV Periodontitis

NCT ID: NCT07053865

Last Updated: 2025-09-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-06-27

Study Completion Date

2025-07-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This study aims to investigate the association between periodontitis Stage III and IV and the intensity and duration of sleep bruxism episodes. Surface electromyography (EMG) of the masseter muscle will be used to instrumentally assess sleep bruxism in patients with and without periodontal disease

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The purpose of this cross-sectional study is to evaluate whether patients with Stage III and IV periodontitis exhibit differences in sleep bruxism activity compared to individuals without periodontal disease. Participants will undergo comprehensive periodontal assessment and 24-hour EMG recording of the masseter muscle using a portable device. Bruxism activity will be quantified using the Bruxism Work Index (BWI) and Bruxism Time Index (BTI). The study aims to clarify the potential relationship between periodontal inflammation and masticatory muscle activity during sleep, following standardized diagnostic and recording protocols

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Bruxism Periodontitis Sleep Bruxism

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Periodontitis Group

Patients diagnosed with Stage III or IV periodontitis according to the 2017 World Workshop classification. Participants will undergo full-mouth periodontal examination and 24-hour surface EMG recording of the masseter muscle to assess sleep bruxism activity.

Surface Electromyography (dia-BRUXO)

Intervention Type DEVICE

Participants will undergo 24-hour surface electromyographic recording of the left masseter muscle using the dia-BRUXO portable device to quantify sleep bruxism activity through Bruxism Work Index (BWI) and Bruxism Time Index (BTI).

Healthy Control Group

Participants without clinical signs of periodontal disease, matched by age and sex to the periodontitis group. They will also receive a full-mouth periodontal screening and 24-hour surface EMG recording of the masseter muscle for sleep bruxism assessment.

Surface Electromyography (dia-BRUXO)

Intervention Type DEVICE

Participants will undergo 24-hour surface electromyographic recording of the left masseter muscle using the dia-BRUXO portable device to quantify sleep bruxism activity through Bruxism Work Index (BWI) and Bruxism Time Index (BTI).

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Surface Electromyography (dia-BRUXO)

Participants will undergo 24-hour surface electromyographic recording of the left masseter muscle using the dia-BRUXO portable device to quantify sleep bruxism activity through Bruxism Work Index (BWI) and Bruxism Time Index (BTI).

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Age between 28 and 50 years
* Ability to perform adequate oral hygiene
* Willingness to participate and sign informed consent
* For periodontitis group: Diagnosis of Stage III or IV periodontitis
* For control group: Absence of periodontal disease

Exclusion Criteria

* Use of removable dentures
* Ongoing orthodontic treatment
* Temporomandibular disorders (TMD) or orofacial pain
* Use of medications affecting muscle activity
* Systemic or psychiatric disorders
* Diabetes
Minimum Eligible Age

28 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

University of Siena

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Nicola Discepoli

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Nicola Discepoli, DDS, PhD

Role: PRINCIPAL_INVESTIGATOR

Department of Medical Biotechnologies, University of Siena

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

AOUS

Siena, , Italy

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Italy

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

PB001

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Bruxism and Diadinamic Current
NCT07241728 RECRUITING NA