Comparison of the Effectiveness of Articaine Local Infusion and Lidocaine Nerve Block in Lower Posterior Tooth Extraction.

NCT ID: NCT07048834

Last Updated: 2025-07-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-03-15

Study Completion Date

2022-05-17

Brief Summary

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In this study 60 adult patients will participate and divided into two groups (30 for each). The first group will be anesthetized using 2 % lidocaine with 1:80,000 adrenaline by inferior alveolar nerve block technique, while the second group will be anesthetized using 4 % articaine with 1:100,000 adrenaline via buccal and lingual infiltration technique in posterior teeth area. Then patients will wait for five minutes after receiving a local anesthetic injection before extraction could begin.

After that every tooth's buccal, lingual, mesial, and distal surfaces will be examined using a disposable dental explorer. Then by visual analog scale (VAS) which provides accessible, sensitive, valid, and reliable means to measure a variety of subjective parameters the pain score will be registered during tooth extraction.

Female patients who are breastfeeding or pregnant, those allergic to local anesthetics, lacking full mental ability, currently taking opioids, having an infection at the extraction site, or those under the influence of medicines that alter their perception of pain will be excluded from the study.

Detailed Description

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Conditions

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Anesthesia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

SINGLE

Participants

Study Groups

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patients anesthetized by 2 % lidocaine with 1:80,000 adrenaline by inferior alveolar nerve block.

This group of (30 patients) will be anesthetized using 2 % lidocaine with 1:80,000 adrenaline by inferior alveolar nerve block technique, Then patients will wait for five minutes after receiving a local anesthetic injection before extraction could begin.

After that every tooth's buccal, lingual, mesial, and distal surfaces will be examined using a disposable dental explorer. Then by visual analog scale (VAS) which provides accessible, sensitive, valid, and reliable means to measure a variety of subjective parameters the pain score will be registered during tooth extraction

Group Type OTHER

lidocaine local anesthetic drug

Intervention Type OTHER

Lidocaine Nerve Block technique

anesthetized by 4 % articaine with 1:100,000 adrenaline via buccal and lingual infiltration.

This group (of 30 patients) will be anesthetized using 4 % articaine with 1:100,000 adrenaline via buccal and lingual infiltration technique in posterior teeth area. Then patients will wait for five minutes after receiving a local anesthetic injection before extraction could begin.

After that every tooth's buccal, lingual, mesial, and distal surfaces will be examined using a disposable dental explorer. Then by visual analog scale (VAS) which provides accessible, sensitive, valid, and reliable means to measure a variety of subjective parameters the pain score will be registered during tooth extraction.

Group Type OTHER

articaine local anesthetic drug

Intervention Type OTHER

Articaine Local Infusion technique

Interventions

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lidocaine local anesthetic drug

Lidocaine Nerve Block technique

Intervention Type OTHER

articaine local anesthetic drug

Articaine Local Infusion technique

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* clinically healthy patients

Exclusion Criteria

* Breastfeeding or pregnant
* Allergic to local anaesthetics drugs
* Lack full mental ability
* Infection at the extraction site
* Patient who currently taking opioids or under the influence of medicines that alter their perception of pain are not candidates for tooth extraction
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Amjed Fouad Hussein

OTHER

Sponsor Role lead

Responsible Party

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Amjed Fouad Hussein

Assistant Lecturer

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Ahl Al Bayt University

Karbala, , Iraq

Site Status

Countries

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Iraq

References

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Webster S Jr, Drum M, Reader A, Fowler S, Nusstein J, Beck M. How Effective Is Supplemental Intraseptal Anesthesia in Patients with Symptomatic Irreversible Pulpitis? J Endod. 2016 Oct;42(10):1453-7. doi: 10.1016/j.joen.2016.07.002.

Reference Type BACKGROUND
PMID: 27663614 (View on PubMed)

Related Links

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Other Identifiers

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1419

Identifier Type: -

Identifier Source: org_study_id

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