Comparison of Articaine and Prilocaine for Extraction of Maxillary Teeth

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

95 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-09-20

Study Completion Date

2018-06-20

Brief Summary

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Ninety-five patients, aged between 16 and 70 years old, were included in this study. Patients were divided into two groups. Group one received Articaine 4% with 1:00.000 Adrenalines. Group two received Prilocaine with 3% Felypressin (0.03 I.U. per ml). Onset time of anaesthesia was objectively evaluated by using electronic pulp testing.

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Detailed Description

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85 patients in this study had successful local anaesthetic followed by extraction within the study duration time (10 minutes). However, there were six patients with failure anaesthesia (5 in prilocaine group and 1 in articaine group). By application Person's Chi-square test (x2), there were no significant differences in the number of the episodes of the anaesthetic success between articaine and prilocaine groups at time intervals (P-value = 0.5). T- test showed there have been no important variations within the mean onset time of anaesthesia for articaine and prilocaine buccal infiltrations (P-value =0.1).

Conditions

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Overcoming the Failure of Anaesthesia Maxillary Teeth Dental Extraction

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

double blinded randomised trial

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Articaine 4% with 1:00.000 Adrenaline

if the patient was in articaine group, buccal infiltration technique was applied by inserting a short needle at the height of buccal sulcus along the long axis of the subject tooth for extraction.

Group Type ACTIVE_COMPARATOR

Articaine 4%

Intervention Type DRUG

Articaine 4% is dental local anaesthetic agent

Adrenalin

Intervention Type DRUG

adrenaline is a vasoconstrictor

Prilocaine with 3% Felypressin (0.03 I.U. per ml)

if the patient was in prelocaine group, buccal infiltration technique was applied by inserting a short needle at the height of buccal sulcus along the long axis of the subject tooth for extraction.

Group Type ACTIVE_COMPARATOR

Prilocain 3%

Intervention Type DRUG

prilocaine is dental local anaesthetic agent

Felypressin

Intervention Type DRUG

Felypressin is a vasoconstrictor

Interventions

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Articaine 4%

Articaine 4% is dental local anaesthetic agent

Intervention Type DRUG

Prilocain 3%

prilocaine is dental local anaesthetic agent

Intervention Type DRUG

Adrenalin

adrenaline is a vasoconstrictor

Intervention Type DRUG

Felypressin

Felypressin is a vasoconstrictor

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients have one or two upper teeth for extraction, subject tooth or its adjacent must be vital, healthy patient or patient with mild systemic diseases (class I or II according to American Society of Anesthesiology).