EVALUATION OF NEUTROPHIL FLUORESCENCE IN PATIENTS WITH DISSEMINATED INTRAVASCULAR COAGULATION ASSOCIATED WITH SEPTIC SHOCK

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-07-01

Study Completion Date

2027-08-01

Brief Summary

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Neutrophil fluorescence could be a reliable and early diagnostic marker of disseminated intravascular coagulation septic DIC, which can be used routinely. The objective of the investigators is to define the optimal threshold of neutrophil fluorescence associated with a sensitivity of at least 90% for the diagnosis of DIC.

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Detailed Description

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Conditions

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DISSEMINATED INTRAVASCULAR COAGULATION ASSOCIATED WITH SEPTIC SHOCK

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Blood sampling collection

CBC performed on the background of an EDTA tube, collected routinely allowing neutrophil fluorescence measurements.

This tube will then be passed over on the automaton for a CBC measurement with leukocyte differentiation.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Male or female ≥ 18 years of age
* Patient admitted to intensive care for septic shock
* Patient affiliated to a social security scheme or entitled to it
* Non-opposition by the patient or a relative in the event that the patient is not in a state to express his or her consent or inclusion in an emergency procedure in the event that the patient is not in a state to express his or her opinion and no relative of the patient can be reached.

Exclusion Criteria

* Dying patient on the day of inclusion
* Cirrhosis Child Pugh C
* Neutropenia (\<500 mm3)
* Patient under judicial protection
* Patient under guardianship or curatorship
* Pregnancy
* Breastfeeding

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No