Immune-Nutritional Scores and Sleep Quality After Total Abdominal Hysterectomy

NCT ID: NCT07038564

Last Updated: 2025-06-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-06-25

Study Completion Date

2025-09-15

Brief Summary

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This prospective observational study aims to evaluate the relationship between preoperative immune-nutritional status and postoperative sleep quality in women undergoing total abdominal hysterectomy under general anesthesia. Immune-nutritional scores, including the Prognostic Nutritional Index (PNI) and Hemoglobin-Albumin-Lymphocyte-Platelet (HALP) score, will be calculated using routine preoperative blood parameters. Postoperative sleep quality will be assessed using the Richards-Campbell Sleep Questionnaire (RCSQ). Secondary outcomes include postoperative pain scores and patient satisfaction. The study will enroll 60 patients and seeks to determine whether preoperative physiological markers can predict subjective recovery parameters such as sleep and comfort, potentially contributing to personalized perioperative care.

Detailed Description

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Conditions

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Immune-Nutritional Indexes (PNI, HALP) Postoperative Sleep Quality

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Immune-Nutritional Scoring and Postoperative Sleep Assessment

Routine preoperative laboratory data (hemoglobin, albumin, lymphocyte, platelet) will be used to calculate immune-nutritional scores (HALP, PNI). Postoperative sleep quality will be assessed with the Richards-Campbell Sleep Questionnaire (RCSQ).

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Female patients aged 18-70
* ASA physical status I-III
* Undergoing elective total abdominal hysterectomy under general anesthesia
* Available complete blood count and biochemistry results within 24 hours preoperatively
* Planned to stay at least one night postoperatively
* Sufficient cognitive ability to understand and complete questionnaires
* Provided written informed consent

Exclusion Criteria

* History of neurological or psychiatric illness
* Diagnosed sleep disorders
* Current use of sedative or hypnotic medications
* Undergoing additional surgical procedures during operation
* Requiring postoperative intensive care
* Operated under spinal or epidural anesthesia
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Istinye University

OTHER

Sponsor Role lead

Responsible Party

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İlke Dolgun

Assoc. prof

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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ilke dolgun

Role: CONTACT

+905555485632

References

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Li J, Guo Q, Ye X, Lin J, Yi C, Mao H, Yang X, Yu X. Prevalence and risk factors of sleep disturbance in continuous ambulatory peritoneal dialysis patients in Guangzhou, southern China. Int Urol Nephrol. 2012 Jun;44(3):929-36. doi: 10.1007/s11255-011-0060-5. Epub 2011 Sep 30.

Reference Type RESULT
PMID: 21960370 (View on PubMed)

Ishiguro T, Aoyama T, Ju M, Kazama K, Fukuda M, Kanai H, Sawazaki S, Tamagawa H, Tamagawa A, Cho H, Hara K, Numata M, Hashimoto I, Maezawa Y, Segami K, Oshima T, Saito A, Yukawa N, Rino Y. Prognostic Nutritional Index as a Predictor of Prognosis in Postoperative Patients With Gastric Cancer. In Vivo. 2023 May-Jun;37(3):1290-1296. doi: 10.21873/invivo.13207.

Reference Type RESULT
PMID: 37103068 (View on PubMed)

Farag CM, Antar R, Akosman S, Ng M, Whalen MJ. What is hemoglobin, albumin, lymphocyte, platelet (HALP) score? A comprehensive literature review of HALP's prognostic ability in different cancer types. Oncotarget. 2023 Feb 25;14:153-172. doi: 10.18632/oncotarget.28367.

Reference Type RESULT
PMID: 36848404 (View on PubMed)

Para E, Uslu N. Cerrahi hastalarında ameliyat sonrası uyku kalitesi ve uyku düzenini etkileyen etmenler. CBU Sağlık Bilimleri Dergisi. 2022;9(3):443-450. doi:10.34087/cbusbed.1034063.

Reference Type RESULT

Other Identifiers

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TAH PNI HALP

Identifier Type: -

Identifier Source: org_study_id

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