Ultrasound Guided Versus Surgical Rectus Sheath Block Versus Local Anesthesia Infiltration for Postoperative Analgesia in Patients Undergoing Total Abdominal Hysterectomy

NCT ID: NCT06837532

Last Updated: 2025-02-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

90 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-02-20

Study Completion Date

2025-08-01

Brief Summary

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The aim of this work is to compare the efficacy and safety of the effectiveness and safety of ultrasound-guided surgical rectus sheath block and local anesthetic infiltration for postoperative analgesia in patients undergoing total abdominal hysterectomy.

Detailed Description

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Total abdominal hysterectomy (TAH) is a commonly performed major surgical procedure that results in substantial postoperative pain and discomfort.

Local anesthetic infiltration (LAI) at the end of surgery is one of the most common technique employed in laparotomies for postoperative analgesia.

Rectus sheath block (RSB) has been used as a part of multimodal analgesia, especially when neuraxial techniques are unsuitable.The RSB was used to achieve peri-operative relaxation of the anterior abdominal wall.

Conditions

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Ultrasound Surgical Rectus Sheath Block Local Anesthesia Infiltration Postoperative Analgesia Total Abdominal Hysterectomy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Ultrasound-guided rectus sheath block group

Patients will receive ultrasound-guided rectus sheath block (20 ml bupivacaine 0.25%) bilaterally at the end of surgery.

Group Type EXPERIMENTAL

Ultrasound-guided rectus sheath block

Intervention Type DRUG

Patients will receive ultrasound-guided rectus sheath block (20 ml bupivacaine 0.25%) bilaterally at the end of surgery.

Surgical rectus sheath block group

Patients will receive a surgical rectus sheath block (20 ml bupivacaine 0.25%) bilaterally at the time of closure.

Group Type EXPERIMENTAL

Surgical rectus sheath block

Intervention Type DRUG

Patients will receive a surgical rectus sheath block (20 ml bupivacaine 0.25%) bilaterally at the time of closure.

Local anesthesia infiltration group

Patients will receive local anesthesia infiltration at the end of surgery.

Group Type EXPERIMENTAL

Local anesthesia infiltration

Intervention Type DRUG

Patients will receive local anesthesia infiltration at the end of surgery.

Interventions

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Ultrasound-guided rectus sheath block

Patients will receive ultrasound-guided rectus sheath block (20 ml bupivacaine 0.25%) bilaterally at the end of surgery.

Intervention Type DRUG

Surgical rectus sheath block

Patients will receive a surgical rectus sheath block (20 ml bupivacaine 0.25%) bilaterally at the time of closure.

Intervention Type DRUG

Local anesthesia infiltration

Patients will receive local anesthesia infiltration at the end of surgery.

Intervention Type DRUG

Other Intervention Names

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Bupivacaine Bupivacaine Bupivacaine

Eligibility Criteria

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Inclusion Criteria

* Age from 18 to 65 years old.
* American Society of Anesthesiologists (ASA) physical status I - II.
* Patients scheduled for elective total abdominal hysterectomy under general anesthesia.

Exclusion Criteria

* Hepatic, renal or cardiac disease.
* Any known allergy to local anesthetic.
* Physical or mental conditions which may vaguely measure postoperative pain following surgery.
* History of chronic use of analgesic as nonsteroidal anti-inflammatory drugs (NSAIDs) or central nervous system (CNS) depressants as antiepileptic, and bleeding disorders.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Ain Shams University

OTHER

Sponsor Role lead

Responsible Party

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Sarah Ahmed

Lecturer of Anesthesia, Intensive care, and pain management, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Ain Shams University

Cairo, , Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Sarah A Afifi, MD

Role: CONTACT

0501035864

Facility Contacts

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Sarah A Afifi, MD

Role: primary

0501035864

Other Identifiers

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FMASU R23/2025

Identifier Type: -

Identifier Source: org_study_id

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