Prospective Observational Analysis of Circulating Endocan Levels in Patients Presenting With Acute Diverticulitis

NCT ID: NCT07027007

Last Updated: 2025-06-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-09-30

Study Completion Date

2027-09-30

Brief Summary

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Quantify the level of endocan in blood samples collected from patients with acute diverticulitis in the emergency department. Determine if endocan levels are correlated with the severity of diverticulitis according to the WSES classification. Assess whether patients requiring emergency surgical intervention have higher endocan values compared to others.

Detailed Description

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Conditions

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Diverticulitis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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patients with acute diverticulitis

Patients admitted to the emergency department with acute diverticulitis classified according to WSES statements.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Patients who have signed informed consent
* Patients who are affected by acute diverticulitis after clinical evaluation and imaging (i.e. u.s. or CeCT)

Exclusion Criteria

* Immunosuppressed patients
* Patients suffering chronic inflammatory diseases
* Patients with concomitant malignancy, cardiac, renal and haepatic failure
* History of major vascular surgery (aneurysmectomy)
* Pregnant women
* Patients participating in other studies that may interfere with the outcome of the intervention.
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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IRCCS Ospedale San Raffaele

OTHER

Sponsor Role lead

Responsible Party

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Luca Ghirardelli

MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Emergency Department IRCCS San Raffaele

Milan, milano, Italy

Site Status

Countries

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Italy

Facility Contacts

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Luca Ghirardelli, MD

Role: primary

+393282342663

Other Identifiers

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DIVENDO STUDY

Identifier Type: -

Identifier Source: org_study_id

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