Neutrophil-to Lymphocyte and Monocyte-to-Lymphocyte Ratios in Exudative Pleural Effusion

NCT ID: NCT07003204

Last Updated: 2025-06-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-05-11

Study Completion Date

2025-05-26

Brief Summary

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Exudative pleural effusion (EPE) presents a diagnostic challenge, requiring accurate biomarkers to predict outcomes and guide treatment. The neutrophil-to-lymphocyte ratio (NLR) and monocyte-to-lymphocyte ratio (MLR) in pleural fluid are emerging as potential prognostic markers. We aimed to assess the diagnostic and prognostic utility of pleural fluid NLR and MLR in EPE.

Detailed Description

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Pleural fluid NLR and MLR are reliable biomarkers for diagnosing malignant pleural effusion and predicting poorer survival outcomes. These ratios may be useful in clinical practice, especially in resource-limited settings, to guide decision-making in the management of pleural effusions.

Conditions

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Effusion

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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only one group of patients

prospective cohort randomized control study

medical thoracoscopy

Intervention Type PROCEDURE

pleural fluid aspiration and cellular analysis

Interventions

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medical thoracoscopy

pleural fluid aspiration and cellular analysis

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* adult patients aged 18-80 years with an EPE diagnosis confirmed by thoracentesis.
Minimum Eligible Age

18 Months

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Alexandria University

OTHER

Sponsor Role lead

Responsible Party

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Mohamed Sabry

Lecturer of chest diseases

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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mohamed Sabry eltarhony, lecturer

Role: PRINCIPAL_INVESTIGATOR

Alexandria University

Locations

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Chest Department -Faculty of Medicine

Alexandria, Egypt, Egypt

Site Status

Countries

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Egypt

Study Documents

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Document Type: Clinical Study Report

very good

View Document

Related Links

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https://pmc.ncbi.nlm.nih.gov/articles/PMC8075197/

https://pmc.ncbi.nlm.nih.gov/articles/PMC8075197/

Other Identifiers

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lymphocyte- monocyte- exudate

Identifier Type: -

Identifier Source: org_study_id

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