Pleural Tissue Culture Versus Pleural Fluid Culture in Infected Effusion
NCT ID: NCT07140003
Last Updated: 2025-08-24
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ENROLLING_BY_INVITATION
NA
30 participants
INTERVENTIONAL
2025-07-01
2025-10-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
DIAGNOSTIC
NONE
Study Groups
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one group of patients will undergo pleural fluid culture taken by ultrasound chest by 18 gauge needl
microbiological culture of the fluid
pleural biopsy
To assess whether pleural tissue culture can improve the identification of causative organisms in pleural infections (using the pleural fluid culture), which can aid in selecting appropriate antimicrobial therapy and improve treatment outcomes, thus may provide valuable insights into the utility of pleural tissue culture in managing pleural infection and may guide clinicians in selecting the most appropriate diagnostic approach.
sonographic guided pleural tissue culture
pareital pleural biobsy will be taken from the posterior costal pleura by ultrasound via true cut biopsy 12 french and tissue will be sent to the micro alab
pleural biopsy
To assess whether pleural tissue culture can improve the identification of causative organisms in pleural infections (using the pleural fluid culture), which can aid in selecting appropriate antimicrobial therapy and improve treatment outcomes, thus may provide valuable insights into the utility of pleural tissue culture in managing pleural infection and may guide clinicians in selecting the most appropriate diagnostic approach.
Interventions
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pleural biopsy
To assess whether pleural tissue culture can improve the identification of causative organisms in pleural infections (using the pleural fluid culture), which can aid in selecting appropriate antimicrobial therapy and improve treatment outcomes, thus may provide valuable insights into the utility of pleural tissue culture in managing pleural infection and may guide clinicians in selecting the most appropriate diagnostic approach.
Eligibility Criteria
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Inclusion Criteria
* Exudate neutrophilic pleural fluid aspirate, or met at least one or more of the following criteria: grossly frank purulent, gram stain positive for bacteria, bacterial culture positive, acidic with a pH \<7.20, low pleural fluid glucose (\<55mg/dL), and CT evidence of pleural infection. Exclusion criteria: Pleural infections by Mycobacterium tuberculosis.Malignant effusion.Coagulation defects.
ALL
Yes
Sponsors
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Alexandria University
OTHER
Responsible Party
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Principal Investigators
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mohamed sabry eltarhony, lecturer
Role: PRINCIPAL_INVESTIGATOR
Alexandria University
hatem essam hamed, lecturer
Role: STUDY_DIRECTOR
Alexandria University
Locations
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Chest Department -Faculty of Medicine
Alexandria, Chest Department, Egypt
Countries
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Related Links
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national library of information
Other Identifiers
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pleura,tissue culture,sonograp
Identifier Type: -
Identifier Source: org_study_id
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