MedDataX Logo

Liberal Versus Restrictive Transfusion Strategy in Patients With Upper Git Bleeding

NCT ID: NCT06996613

Last Updated: 2025-05-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-05-22

Study Completion Date

2025-11-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Comparison between the effects and results of the two strategies of blood transfusion, liberal and restrictive in patients with upper Git bleeding

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Transfusion in Gastrointestinal Bleeding

NCT02105532

Gastrointestinal Hemorrhage
COMPLETED PHASE2/PHASE3

Tranxemic Acid and Vitamin K Injection to Control Upper Gastrointestinal Bleeding in Cirrhotic Patients

NCT06881628

Upper Gastrointestinal Bleeding (UGIB) Variceal Bleeding Cirrhosis
RECRUITING PHASE4

Optimization Strategies for Blood Transfusion Protocols in the Emergency Treatment of Hemorrhagic Shock

NCT07129031

Hemorrhage Hemorrhagic Shock Upper Gastrointestinal Bleeding (UGIB)
NOT_YET_RECRUITING PHASE3

Efficacity and Safety of Tranexamic Acid in Cirrhotic Patients Presenting With Acute Upper Gastrointestinal Bleeding

NCT03023189

Upper Digestive Bleeding Cirrhosis
UNKNOWN PHASE4

Transfusion Requirements in Gastrointestinal (GI) Bleeding

NCT00414713

Upper Gastrointestinal Bleeding Cirrhosis Portal Hypertension
UNKNOWN PHASE4

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Comparison between safety, efficacy and mortality rate in the two strategies of blood transfusion, liberal(target Hb 9-11g/dl) and restrictive(target Hb 7-9 g/dl )in patients with upper Git bleeding in sohag university hospital, and how other risk factors as liver cirrhosis , CKD,and cause of bleeding in the patient affect results and expected complications that may be occur after blood transfusion

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Upper Git Bleeding

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Upper endoscopy

It's a diagnostic endoscope to show the cause of upper Git bleeding

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* all patients presented by upper GIT bleeding and their CBC show anemia and need blood transfusion

Exclusion Criteria

* all patients less than 18 years and patients have anemia and received blood transfusion by another causes other than GIT bleeding
Minimum Eligible Age

18 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Sohag University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Reham Elsayed Ibrahim

resident doctor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Reham Elsayed

Role: STUDY_CHAIR

Sohg university hospital

Reham Elsayed

Role: PRINCIPAL_INVESTIGATOR

Tertiary hospital

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Faculty of medicine sohag university

Sohag, , Egypt

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Egypt

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Reham Elsayed

Role: CONTACT

[email protected]
01148187498

Reham Elsayed

Role: CONTACT

[email protected]
01148287498

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Reham Elsayed

Role: primary

[email protected]
01148187498

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

Soh-Med--25-5-12MS

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Different Methods of Tranexamic Acid Application in Controlling Peri Operative Bleeding in Gynecomastia Surgery
NCT06509256 NOT_YET_RECRUITING EARLY_PHASE1
Safety and Efficacy of Prophylactic Arterial Embolization in the Treatment of Angiography-negative Acute Upper Gastrointestinal Bleeding
NCT05550649 UNKNOWN NA
Gastrointestinal Bleeding Management
NCT02403076 UNKNOWN
Rotational Thromboelastometry [ROTEM] vs Thromboelastography [TEG] Guided Blood Component Use in Patients With Cirrhosis of Liver With Non-variceal Bleeding.
NCT06153082 RECRUITING NA
Hepato-duodenal Ligament Occlusion and Classic Technique in Liver Transplant
NCT04265157 UNKNOWN
Terlipressin Infusion During Whipple Procedure: Effect on Blood Loss and Transfusion Needs
NCT03572088 COMPLETED PHASE2
Tranexamic Acid for Upper Gastrointestinal Bleeding
NCT01713101 UNKNOWN PHASE3
Transfusion Strategies for Pediatric Liver Transplantation
NCT02951013 UNKNOWN NA
Role of Tranexamic Acid Versus Uterine Cooling at Caesarean Section
NCT02780245 COMPLETED PHASE4
Intraoperative Phlebotomies and Bleeding in Liver Transplantation
NCT04826666 COMPLETED
the Use of Tranexamic Acid to Prevent the Bleeding in Bariatric Surgery
NCT07187258 COMPLETED PHASE4
Management of Gastrointestinal Bleeding Under Direct Oral Anticoagulants
NCT07333144 RECRUITING
Management of Coagulopathy in Cirrhotic Patients Undergoing Invasive Procedures
NCT02987712 UNKNOWN NA
Efficacy of Tranexamic Acid in Upper Gastrointestinal Bleeding
NCT04788121 UNKNOWN PHASE3
Conventional Versus Point-of-care Based Coagulation Management
NCT00997841 COMPLETED PHASE4
Role Of Different Prophylactic Doses Of Intravenous Tranexamic Acid In Reducing Blood Loss At Caesarean Section
NCT02739815 COMPLETED PHASE4
Intravenous Tranexamic Acid Versus Pericervical Tourniquet To Decrease Blood Loss In Trans-Abdominal Myomectomy
NCT02733952 UNKNOWN PHASE3
Liberal Transfusion Strategy in Elderly Patients
NCT03369210 ACTIVE_NOT_RECRUITING PHASE3
Efficacy of Topical Versus Intravenous Tranexamic Acid in Controlling Blood Loss
NCT06188052 RECRUITING PHASE4
Suction Drainage in the Management of Peri-operative Bleeding in Total and Unicomcompartmental Knee Arthroplasty
NCT04508101 UNKNOWN
Transfusion HeAd NecK Surgery
NCT03910816 COMPLETED
Safety and Efficacy of Intravenous Tranexamic Acid in Endoscopic Transurethral Resections in Urology
NCT02653261 COMPLETED PHASE4
Precise Endoscopic Application of Tranexamic Acid and Sucralfate in Gastrointestinal Bleeding: A Randomized Controlled Trial
NCT06421389 COMPLETED NA
Systematic Analysis of a Standardized Questionnaire to Detect Possible Bleeding Disorders and Its Impact on Perioperative Hemostasis Management
NCT04993170 COMPLETED
Blood Management Program in the Post - Operative Period.
NCT02149069 UNKNOWN