Hepato-duodenal Ligament Occlusion and Classic Technique in Liver Transplant

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-03-31

Study Completion Date

2022-09-30

Brief Summary

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Liver transplantation was historically associated with massive blood loss. Many factors have contributed to the decline in bleeding and transfusion in the past two decades including refinement of surgical techniques, anesthetics management and the use of point of care guided goal-directed hemostatic therapies. Increasing awareness of the adverse associations of allogenic transfusion has driven the quest for transfusion-free transplantation. Pre-operative management of preoperative anemia and targeted correction of coagulopathy is done to decrease blood transfusion. Liver transplantation is associated with the potential for massive operative blood loss, which has been recognized as one of the main causes of morbidity and mortality after liver transplantation. Therefore, a fine surgical procedure to reduce intraoperative hemorrhage is necessary for favorable outcomes of liver transplantation.

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Detailed Description

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Conditions

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Liver Transplant

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Early occlusion of hepatoduodenal ligament

Early occlusion of hepatoduodenal ligament during mobilization of the liver of the recipient by using portal vein clamp or occlusive temporary bands.

Surgical technique surgical occlusion

Intervention Type PROCEDURE

Occlusion of hepatoduodenal ligament by clamp or occlusive bands

classical occlusion of hepatoduodenal ligament

classical occlusion of hepatoduodenal ligament after mobilization of the liver of the recipient immediately before explantation by suing of portal vein clamp

Surgical technique surgical occlusion

Intervention Type PROCEDURE

Occlusion of hepatoduodenal ligament by clamp or occlusive bands

Interventions

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Surgical technique surgical occlusion

Occlusion of hepatoduodenal ligament by clamp or occlusive bands

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* All patients undergoing Living Donor Liver Transplantation accepted according to hospital protocol
* All patients with liver Cirrhosis who have Porto systemic collaterals based on ct angiography