ILY Robotic System vs Manual Flexible Ureteroscopy for Kidney Stone Treatment

NCT ID: NCT06996587

Last Updated: 2025-05-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

152 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-05-01

Study Completion Date

2027-08-31

Brief Summary

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The goal of this clinical trial is to compare the efficacy, ergonomics, and safety of robotic versus manual flexible ureteroscopy (fURS) for kidney stone treatment in adult patients undergoing laser lithotripsy.

* Does robotic-assisted lithotripsy using the ILY® robot have the same efficacy as the manual fURS in treating kidney stones?
* Is robotic flexible ureteroscopy associated with similar or improved safety outcomes, including perioperative and 30-day postoperative complication rates?
* Does the robotic system offer improved ergonomics, lower surgeon radiation exposure, and favorable intraoperative metrics compared to manual flexible ureteroscopy? Researchers will compare the ILY robotic system with manual fURS to see if robotic intervention can match or improve clinical and ergonomic outcomes.

Participants will:

* Be randomly assigned to undergo laser lithotripsy with either the ILY robot or manual flexible ureteroscopy
* Complete standard pre- and postoperative assessments
* Undergo evaluation for stone-free status using a non-contrast CT scan at 30 days postoperatively
* Undergo evaluation for postoperative complications

Detailed Description

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Conditions

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Kidney Stones Urolithiasis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Robotic-Assisted fURS Group using the ILY Robot

Participants undergo flexible ureteroscopy using the ILY® robotic system.

Group Type EXPERIMENTAL

Robotic-Assisted Flexible Ureteroscopy

Intervention Type PROCEDURE

Use of the ILY® robotic system to perform flexible ureteroscopy.

Manual fURS Group

Participants undergo standard manual flexible ureteroscopy.

Group Type ACTIVE_COMPARATOR

Manual Flexible Ureteroscopy

Intervention Type PROCEDURE

Conventional flexible ureteroscopy performed manually by the surgeon.

Interventions

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Robotic-Assisted Flexible Ureteroscopy

Use of the ILY® robotic system to perform flexible ureteroscopy.

Intervention Type PROCEDURE

Manual Flexible Ureteroscopy

Conventional flexible ureteroscopy performed manually by the surgeon.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Males or females ≥ 18 years old
* Patients with a normal pelvicalyceal anatomy
* Patients with renal stone diagnosis confirmed by noncontrast computed tomography regardless of stone size, location, and multiplicity
* ASA score I-III
* Intact mental and cognitive ability to provide informed consent and willingness to participate in the study with 30-day follow-up

Exclusion Criteria

* Children \< 18 and pregnant women
* Patients with anatomically anomalous kidneys, known case of stricture or stenosis, or recent 3-month history of ureteroscopy (DJ stent placement only will be accepted) or known history of complicated ureteroscopy
* Patients in whom stone measurement was not feasible on NCCT or those with concomitant ureteric stones.
* ASA score IV
* Mentally incapacitated patients unable to provide informed consent
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Albert El Hajj

OTHER

Sponsor Role lead

Responsible Party

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Albert El Hajj

Associate Professor of Urology

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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American University of Beirut Medical Center

Beirut, , Lebanon

Site Status RECRUITING

Countries

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Lebanon

Central Contacts

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Albert El Hajj, MD

Role: CONTACT

+961-1-350000 ext. 5246, 5800

Facility Contacts

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Albert El Hajj, MD

Role: primary

+961-1-350000 ext. 5246, 5800

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Document Type: Informed Consent Form

View Document

Other Identifiers

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BIO-2024-0452

Identifier Type: -

Identifier Source: org_study_id

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