Comparison of the Effects of Sugammadex and Neostigmine on Early Extubation, Intensive Care Unit Admission and Length of Stay, and Hospital Costs in Adult Cranial Surgery

NCT ID: NCT06987357

Last Updated: 2025-05-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

112 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-05-01

Study Completion Date

2021-07-31

Brief Summary

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The aim of this study was to retrospectively investigate the effects of sugammadex or neostigmine, which are routinely used after the completion of surgery to antagonize (reverse) neuromuscular blockade in adult patients undergoing cranial surgery under general anesthesia, on early extubation in the operating room, intensive care unit admission and length of stay, length of hospital stay, and hospital costs.

Detailed Description

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Conditions

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Craniectomy Sugammadex Extubation Recovery After Neuromuscular Block Hospital Costs

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Group Neostigmine

No interventions assigned to this group

Group Sugammadex

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Patients from the American Society of Anesthesiology (ASA) I-II-III group,
* over the age of 18,
* who underwent elective surgery,
* underwent general anesthesia with sevoflurane anesthesia from volatile anesthetics,
* used rocuronium as a neuromuscular blocking agent

Exclusion Criteria

* Patients aged 18 and under,
* ASA IV and above,
* who underwent surgery under emergency conditions,
* who have incomplete follow-up form records and electronic media data,
* who were taken to the intensive care unit without neuromuscular blockade antagonism due to long surgery,
* who were treated with a neuromuscular blocking agent other than rocuronium,
* who were treated with a volatile anesthetic other than sevoflurane or with total intravenous anesthesia.
Minimum Eligible Age

19 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Kanuni Sultan Suleyman Training and Research Hospital

OTHER

Sponsor Role lead

Responsible Party

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Naime Yalçın

Specialist

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Kanuni Sultan Suleyman Training and Research Hospital

Istanbul, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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KAEK/2021.04.116

Identifier Type: -

Identifier Source: org_study_id

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