Hypofractionated Radiotherapy With Concomitant Tumor Bed Boost for Breast Cancer

NCT ID: NCT06984250

Last Updated: 2025-05-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

315 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-02-06

Study Completion Date

2030-02-28

Brief Summary

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Hypofractionated breast radiotherapy with concomitant tumor bed boost for early breast cancer or ductal breast carcinoma in situ after partial mastectomy

Detailed Description

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Conditions

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Early Breast Cancer Ductal Breast Carcinoma In Situ

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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CBB

Hypofractionated breast radiotherapy following partial mastectomy in patients with early breast cancer or ductal breast carcinoma in situ

Hypofractionated Radiation Therapy

Intervention Type RADIATION

Hypofractionated breast radiotherapy (HFRT) with hybrid techniques combining field-in-field intensity-modulated RT (FIF-IMRT) to the whole breast with inverse-IMRT for concomitant boost

Interventions

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Hypofractionated Radiation Therapy

Hypofractionated breast radiotherapy (HFRT) with hybrid techniques combining field-in-field intensity-modulated RT (FIF-IMRT) to the whole breast with inverse-IMRT for concomitant boost

Intervention Type RADIATION

Other Intervention Names

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Hypofractionated breast radiotherapy with concomitant boost

Eligibility Criteria

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Inclusion Criteria

* Female patients with histologically confirmed early-stage breast cancer (T1-2 and N0-1) or ductal carcinoma in situ (DCIS).
* Patients undergoing breast-conserving surgery
* Age ≥ 20 years
* Karnofsky Performance Status (KPS) ≥70%
* Life expectancy ≥ 5 years
* Adequate renal and hepatic function

Exclusion Criteria

* Pregnant patients
* Patients requiring re-irradiation of the thoracic region
Minimum Eligible Age

20 Years

Maximum Eligible Age

85 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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National Taiwan University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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National Taiwan University Hospital

Taipei, Taiwan, Taiwan

Site Status NOT_YET_RECRUITING

National Taiwan University Hospital Yunlin Branch

Taipei, , Taiwan

Site Status RECRUITING

Countries

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Taiwan

Central Contacts

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Yen-Ting Liu

Role: CONTACT

88697255451

Facility Contacts

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Yen-Ting Liu

Role: primary

886972655451

Yen-Ting Liu

Role: primary

886972655451

Other Identifiers

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113-S0087

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

202110027RINB

Identifier Type: -

Identifier Source: org_study_id

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