Dosimetric Comparison of Three Radiation Techniques for Hypofractionated Whole Breast Radiotherapy in Early Breast Cancer

NCT ID: NCT05394194

Last Updated: 2022-05-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-07-20

Study Completion Date

2025-08-01

Brief Summary

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We aim to compare three different radiation delivery techniques, namely three-dimensional conformal radiation therapy (3D-CRT), intensity modulated radiotherapy (IMRT) and volumetric modulated radiation therapy (VMAT) in left-sided early breast cancer patients.

Detailed Description

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Conditions

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Breast Cancer

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Study Groups

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3DCRT group

In this plan, we will create plans using three dimensional conformal radiotherapy, evaluate organs at risk doses, dose homogeneity and planned target volume coverage. Then compare these parameters with the two other plans.

No interventions assigned to this group

IMRT group

In this plan, we will create plans using intensity modulated radiotherapy (IMRT), evaluate organs at risk doses, dose homogeneity and planned target volume coverage. Then compare these parameters with the two other plans.

No interventions assigned to this group

VMAT plan

In this plan, we will create plans using volumetric modulated radiotherapy (VMAT), evaluate organs at risk doses, dose homogeneity and planned target volume coverage. Then compare these parameters with the two other plans.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* left sided early breast cancer patients. Should have histopathological prove to have invasive breast cancer. Operated by breast conservative surgery. Have no associated comorbidities

Exclusion Criteria

* locally advanced breast cancer. Patients who have total mastectomy. Patients who had previous chest irradiation or known comorbidities.
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Sohag University

OTHER

Sponsor Role lead

Responsible Party

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Alshaymaa Abdelghaffar

Lecturer of Clinical Oncology

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Alshaymaa Abdelghaffar, PhD

Role: PRINCIPAL_INVESTIGATOR

Sohag University

Central Contacts

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Alshaymaa Abdelghaffar, PhD

Role: CONTACT

01006828975 ext. 002

Emad Eldin Nabil Hassan, PhD

Role: CONTACT

01227014556 ext. 002

Other Identifiers

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Soh-Med-22-05-24

Identifier Type: -

Identifier Source: org_study_id

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