Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
140 participants
INTERVENTIONAL
2025-07-07
2029-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
BASIC_SCIENCE
TRIPLE
Study Groups
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Uncertainty-focused single session intervention
This is a digital, self-guided SSI that teaches adults about tolerating and embracing uncertainty in their life. The SSI is based on five elements: 1. An introduction the concept of neuroplasticity; 2. Testimonials from peers describing beliefs that people's thoughts, feelings, and behaviors are malleable, given the brain's capacity for change; 3. Strategies (from cognitive-behavioral therapy) for applying these principles to participants' lives; 4. Further vignettes by peers describing times when they tolerated or embraced uncertainty; 5. An exercise wherein participants provide advice to fictional peers, using newly-gleaned information about uncertainty,
Uncertainty-focused single session intervention
Digitally/computer administered 30-minute self-guided intervention for adults ages 25-60
Maintaining a healthy lifestyle single session intervention
This is a digital, self-guided SSI that teaches adults about the benefits of maintaining a healthy lifestyle (e.g., proper sleep, diet, exercise), emphasizing recommendations by various bodies (e.g., American Medical Association). It is structurally similar to the uncertainty-focused SSI but is designed to mimic what people would receive in their annual physical with a primary care physician. The goals of this intervention is to encourage participants to identify aspects of a healthy lifestyle, and steps they could take towards a healthier lifestyle. This SSI is designed to control for nonspecific aspects of intervention, including engagement in a computer program, reading and writing exercises, and vignettes from peers.
Maintaining a healthy lifestyle single session intervention
Digitally/computer administered 30-minute self-guided intervention for adults ages 25-60
Interventions
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Uncertainty-focused single session intervention
Digitally/computer administered 30-minute self-guided intervention for adults ages 25-60
Maintaining a healthy lifestyle single session intervention
Digitally/computer administered 30-minute self-guided intervention for adults ages 25-60
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
2. Right-handed
3. Ability to read and write English
4. Capacity to provide informed consent
5. Intolerance of uncertainty score ≥ -0.5 standard deviation below the mean (31st percentile)
Exclusion Criteria
2. Personal history of autism spectrum disorder
3. IQ \< 80 as determined by the Wechsler Test of Adult Reading
4. Head injury with greater than 120 seconds loss of consciousness
5. Neurological condition (e.g., epilepsy, Parkinson's, cerebral palsy, history of stroke)
6. Currently pregnant
7. Use of any implanted electrical device (e.g., pacemaker, spinal stimulator, vagal nerve stimulator, Inspire sleep apnea device, etc.).
25 Years
60 Years
ALL
Yes
Sponsors
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National Institute of Mental Health (NIMH)
NIH
Northwestern University
OTHER
Responsible Party
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Brent Rappaport
Assistant Professor
Locations
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Northwestern University
Chicago, Illinois, United States
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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