ART Cycle Outcomes When Only 1 to 3 Oocytes Are Retrieved

NCT ID: NCT06950476

Last Updated: 2025-05-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

3761 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-01-01

Study Completion Date

2023-12-31

Brief Summary

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This is a monocentric retrospective observational study. The study focuses on the women who underwent Assisted Reproductive Technology (ART) cycles with poor ovarian response (POR), defined as \<4 oocytes retrieved.

The objectives of the study are as follows:

* Evaluate clinical pregnancy rate (CPR) and cumulative live birth rate (CLBR) in women with poor ovarian response.
* Evaluate abortion rate in women with poor ovarian response.
* Evaluate the influence of patient characteristics (age, Anti-Müllerian hormone \[AMH\] levels, Antral Follicle Count \[AFC\], Follicle Stimulating Hormone \[FSH\], Body Mass Index \[BMI\]) on women with poor ovarian response.

To address the study objectives, data will be collected using a specific internal web-based database. All oocyte retrieval procedures performed at the Humanitas Fertility Center from January 2010 to December 2023 will be included in the evaluation. Outcomes will be expressed in terms of CLBR, CPR and Abortion Rate.

Detailed Description

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Conditions

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Infertility Assisted Reproductive Technology Oocyte Retrieval

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Interventions

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Oocyte Retrieval

Oocyte retrieval is performed at the end of ovarian stimulation (OS) to collect oocytes for use in IVF or ICSI cycles.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* The study database will include all women who underwent IVF treatment between 2010 and 2023 and were classified as poor ovarian responders, defined as those who retrieved fewer than 4 oocytes following controlled ovarian stimulation.

Exclusion Criteria

* The study database will exclude women who underwent IVF treatment and retrieved more than 3 oocytes following controlled ovarian stimulation.
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Istituto Clinico Humanitas

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Other Identifiers

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POOR RESPONDERS

Identifier Type: -

Identifier Source: org_study_id

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