Anti-Müllerian Hormone is Not Predictive of Pregnancy in Donor Insemination Cycles in Non-infertile Women

NCT ID: NCT03160872

Last Updated: 2017-05-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

143 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-01-01

Study Completion Date

2016-12-15

Brief Summary

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To evaluate if ovarian reserve (measured by means of anti-mullerian hormone -AMH- and antral follicle count -AFC-) can predict pregnancy in donor insemination cycles (dIUI) performed in non-infertile women.

Detailed Description

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Conditions

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Infertility

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Women who undergo donor sperm insemination

Non infertile women who undergo donor sperm insemination cycle

Anti Mullerian Hormone Measurement

Intervention Type DIAGNOSTIC_TEST

Anti Mullerian Hormone was measured in all patients within two months before the first insemination cycle

Interventions

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Anti Mullerian Hormone Measurement

Anti Mullerian Hormone was measured in all patients within two months before the first insemination cycle

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* absence of male partner
* complete azoospermia or the presence of a genetic condition in the partner that made the couple opt for donor sperm
* absence of previous history of infertility.
* d ta on AMH and AFC assessment before the first dIUI cycle.

Exclusion Criteria

* previous history of infertility.
* Presence of any gynaecological condition that could impair the inseminations results:

* endometriosis, hydrosalpinx,…
Minimum Eligible Age

18 Years

Maximum Eligible Age

43 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Fundacion Dexeus

OTHER

Sponsor Role lead

Responsible Party

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Iñaki González Foruria

MD.

Responsibility Role PRINCIPAL_INVESTIGATOR

References

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Catteau-Jonard S, Roux M, Dumont A, Delesalle AS, Robin G, Dewailly D. Anti-Mullerian hormone concentrations and parity in fertile women: the model of oocyte donors. Reprod Biomed Online. 2017 May;34(5):541-545. doi: 10.1016/j.rbmo.2017.02.010. Epub 2017 Mar 1.

Reference Type BACKGROUND
PMID: 28285954 (View on PubMed)

Hvidman HW, Bentzen JG, Thuesen LL, Lauritsen MP, Forman JL, Loft A, Pinborg A, Nyboe Andersen A. Infertile women below the age of 40 have similar anti-Mullerian hormone levels and antral follicle count compared with women of the same age with no history of infertility. Hum Reprod. 2016 May;31(5):1034-45. doi: 10.1093/humrep/dew032. Epub 2016 Mar 9.

Reference Type BACKGROUND
PMID: 26965431 (View on PubMed)

Somigliana E, Lattuada D, Colciaghi B, Filippi F, La Vecchia I, Tirelli A, Baffero GM, Paffoni A, Persico N, Bolis G, Fedele L. Serum anti-Mullerian hormone in subfertile women. Acta Obstet Gynecol Scand. 2015 Dec;94(12):1307-12. doi: 10.1111/aogs.12761. Epub 2015 Sep 16.

Reference Type BACKGROUND
PMID: 26332870 (View on PubMed)

Related Links

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Other Identifiers

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SMD-2016-033

Identifier Type: -

Identifier Source: org_study_id

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