Assessment of Transcatheter Edge-to-Edge Repair in Atrial Functional Mitral Regurgitation (ATRIAL-MR)

NCT ID: NCT06911099

Last Updated: 2025-04-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

1000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-01-01

Study Completion Date

2035-12-31

Brief Summary

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This investigator-initiated, multicenter, international, retrospective registry aims to investigate outcomes of patients with atrial functional mitral regurgitation, as treated in clinical routine.

Detailed Description

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Conditions

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Atrial Functional Mitral Regurgitation Mitral Insufficiency

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Mitral Valve Transcatheter Edge-to-Edge Repair (M-TEER)

Patients who underwent mitral valve transcatheter edge-to-edge repair. All devices may be included.

No interventions assigned to this group

Guideline Directed Medical Therapy

Patients who underwent conservative management with guideline directed medical therapy.

No interventions assigned to this group

Transcatheter Mitral Valve Replacement (TMVR)

Patients who underwent transcatheter mitral valve replacement. All devices may be included.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* functional mitral regurgitation
* left ventricular ejection fraction ≥50%

Exclusion Criteria

* age under 18 years
* known regional wall movement disorders
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital of Cologne

OTHER

Sponsor Role lead

Responsible Party

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Philipp von Stein

MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Christos Iliadis, MD

Role: PRINCIPAL_INVESTIGATOR

Heart Center, Department III of Internal Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Kerpener Straße 62, 50937, Cologne, Germany

Locations

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Montefiore Medical Center

The Bronx, New York, United States

Site Status RECRUITING

St. Michael's Hospital

Toronto, , Canada

Site Status RECRUITING

Bordeaux University Hospital

Bordeaux, , France

Site Status RECRUITING

University Hospital Center of Nantes

Nantes, , France

Site Status RECRUITING

LMU Klinikum

Munich, Bavaria, Germany

Site Status RECRUITING

University Hospital Cologne

Cologne, North Rhine-Westphalia, Germany

Site Status RECRUITING

HDZ Bad Oeynhausen

Bad Oeynhausen, , Germany

Site Status RECRUITING

Heart Center Bonn

Bonn, , Germany

Site Status RECRUITING

University Hospital of Düsseldorf

Düsseldorf, , Germany

Site Status RECRUITING

University Heart and Vascular Center Hamburg

Hamburg, , Germany

Site Status RECRUITING

University Hospital Schleswig-Holstein

Kiel, , Germany

Site Status RECRUITING

Heart Center Leipzig at University of Leipzig

Leipzig, , Germany

Site Status RECRUITING

Heart Center of the University Medical Center Mainz

Mainz, , Germany

Site Status RECRUITING

University Heart Center Ulm

Ulm, , Germany

Site Status RECRUITING

University of Brescia

Brescia, , Italy

Site Status RECRUITING

San Raffaele University Hospital

Milan, , Italy

Site Status RECRUITING

University of Pisa

Pisa, , Italy

Site Status RECRUITING

Hospital Clinic of Barcelona

Barcelona, , Spain

Site Status RECRUITING

Reina Sofia University Hospital

Córdoba, , Spain

Site Status RECRUITING

University Hospital of León

León, , Spain

Site Status RECRUITING

Asturias Central University Hospital

Oviedo, , Spain

Site Status RECRUITING

University Hospital Alvaro Cunqueiro

Vigo, , Spain

Site Status RECRUITING

Countries

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United States Canada France Germany Italy Spain

Central Contacts

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Philipp von Stein, MD

Role: CONTACT

646-321-8145

Christos Iliadis, MD

Role: CONTACT

+49-221-478-32401

Facility Contacts

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Azeem Latib, MD

Role: primary

(718) 920-4212

Andrea Scotti, MD

Role: backup

Neil Fam, MD

Role: primary

416-864-5939

Thomas Modine, MD, PhD

Role: primary

+33557656969

Guillaume Bonnet, MD

Role: backup

Patrice Guérin, MD

Role: primary

+33240998383

Robin Le Ruz, MD

Role: backup

Jörg Hausleiter, Prof. Dr.

Role: primary

+4989440072361

Lukas Stolz, MD

Role: backup

+49 1525 488 9915

Philipp von Stein, MD

Role: primary

646-321-8145

Volker Rudolph, MD

Role: primary

+495731971276

Muhammed Gerçek, MD

Role: backup

+495731971276

Georg Nickenig, MD

Role: primary

+4922828715217

Marcel Weber, MD

Role: backup

+4922828715299

Maximilian Spieker, MD

Role: primary

+492118118801

Sebastian Ludwig, MD

Role: primary

Felix Kreidel, MD

Role: primary

+4943150022801

Tobias Kister, MD

Role: primary

+49341865252536

Ralph Stephan von Bardeleben, MD

Role: primary

+496131178786

Tobias Ruf, MD

Role: backup

Mirjam Kessler, MD

Role: primary

+4973150045001

Matthias Gröger, MD

Role: backup

+4973150045001

Marianna Adamo, MD, PhD

Role: primary

+393897834503

Francesco Maisano, MD

Role: primary

+39226437109

Guido Ascione, MD

Role: backup

Cristina Giannini, MD

Role: primary

+3950996975

Xavier Freixa, MD

Role: primary

+34932275400 ext. 2035

Manuel Pan Álvarez-Ossorio, MD

Role: primary

+34676999144

Tomás Benito-González, MD

Role: primary

+34987237400

Isaac Pascual Calleja, MD

Role: primary

+34917242370

Rodrigo Estevez-Loureiro, MD

Role: primary

+34986811111

Other Identifiers

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24-1121

Identifier Type: -

Identifier Source: org_study_id

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