Effect of Concentrated Growth Factors on Short Implant-Supported Overdentures

NCT ID: NCT06880965

Last Updated: 2025-03-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2/PHASE3

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-08-24

Study Completion Date

2024-12-04

Brief Summary

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The purpose of this study will be to evaluate the effect of concentrated growth factors on stability and radiographic outcome of short implant supported mandibular assisted overdenture

Detailed Description

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A controlled clinical trial will be performed upon patients attending the outpatient clinic of Faculty of Dentistry Tanta University.Ten male patients will be selected for this study. Split mouth study design will be used in this study where, Group I represented the right side of the patients' mandibular posterior region will be restored with short implant in place of first molar and Group II represented the left side of the patients' mandibular posterior region will be restored with short implant in place of first molar and concentrated growth factors. The patients will receive partial mandibular assisted overdenture with O-ring attachment on the implant. Stability of implant and Radiographic evaluations will be carried out for every patient at regular recall visits at the time of insertion, 6 and 12 months

Conditions

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Partially Edentulous Patients

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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short implants assisted over denture in combination with concentrated growth factors

the left side of the patients' mandibular posterior region was restored with short implant in place of first molar by using short implants assisted over denture with concentrated growth factor.

Group Type ACTIVE_COMPARATOR

testing implant stability

Intervention Type DIAGNOSTIC_TEST

testing implant stability by using the periotest device

use concentrated growth factor.

Intervention Type DRUG

short implants assisted over denture in combination with concentrated growth factor.

marginal bone loss calculation

Intervention Type RADIATION

marginal bone loss calculation by digitized periapical radiograph

using mandibular posterior short implants assisted over denture without concentrated growth factors

the right side of the patients' mandibular posterior region was restored with short implant in place of first molar by using short implants assisted over denture without concentrated growth factor.

Group Type PLACEBO_COMPARATOR

testing implant stability

Intervention Type DIAGNOSTIC_TEST

testing implant stability by using the periotest device

marginal bone loss calculation

Intervention Type RADIATION

marginal bone loss calculation by digitized periapical radiograph

Interventions

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testing implant stability

testing implant stability by using the periotest device

Intervention Type DIAGNOSTIC_TEST

use concentrated growth factor.

short implants assisted over denture in combination with concentrated growth factor.

Intervention Type DRUG

marginal bone loss calculation

marginal bone loss calculation by digitized periapical radiograph

Intervention Type RADIATION

Eligibility Criteria

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Inclusion Criteria

* Patients between 20 to 65 years old. Class I Kennedy's classification Good oral hygiene.

Exclusion Criteria

* Bad oral hygiene. Para functional habits ex. (bruxism, clenching,)
Minimum Eligible Age

20 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Tanta University

OTHER

Sponsor Role lead

Responsible Party

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Mai Atef

Lecturer at periodontology and oral medicine department Tanta university

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Sherin F Donia, PHD

Role: PRINCIPAL_INVESTIGATOR

Tanta University

Locations

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Tanta university

Tanta, Gharbia Governorate, Egypt

Site Status

Countries

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Egypt

Other Identifiers

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R-OMPDR-8-23-2

Identifier Type: -

Identifier Source: org_study_id

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