Randomized Controlled Trial of Remote Symptoms Monitoring With Resilience PRO Compared to Care As Usual Only

NCT ID: NCT06867705

Last Updated: 2025-08-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Clinical Phase

PHASE3

Total Enrollment

1458 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-04-01

Study Completion Date

2029-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The goal of this clinical trial is to learn if Resilience PRO, a digital solution performing remote symptoms monitoring, can improve the quality of life of patients with a diagnosis of cancer receiving systemic anticancer treatment.

The main question it aims to answer is:

\- Do patients with a diagnosis of cancer receiving systemic anticancer therapy and using Resilience PRO have an improved quality of life? Researchers will compare patients using Resilience PRO plus care as usual to patients receiving care as usual only.

Participants in the intervention arm will use Resilience PRO, a mobile phone application regularly asking participants about their symptoms. For clinically important symptoms, an alert is sent to the care team that can incorporate that information to timely adjust the care of the participants. Participants both in the control arm and in the intervention arm will further receive care as usual.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Resilience PRO is a digital medical device (dMD CE marked, class IIa) that enables the remote monitoring of patients diagnosed with cancer receiving anticancer systemic therapy. Resilience PRO has been positively evaluated by the French health authorities (HAS, Haute Autorité de Santé) and is registered on the French LATM list (Liste des Activités de Télésurveillance Médicale).

Resilience PRO is a software medical device prescribed by cancer treating physicians to collect electronic patient-reported outcomes (ePRO). The Resilience PRO workflow comprises the following steps:

* Step 1. Collection of ePRO
* Step 2. Intelligent analysis and alerts
* Step 3. Adapted care

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Cancer

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Remote Symptoms Monitoring with Resilience PRO

Resilience PRO will be added on top of conventional care

Group Type EXPERIMENTAL

Resilience PRO

Intervention Type DEVICE

The patient will use Resilience PRO remote symptoms monitoring.

Usual care without Remote Symptoms Monitoring

Conventional care only

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Resilience PRO

The patient will use Resilience PRO remote symptoms monitoring.

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Age: Adults ≥ 18 years.
* Informed Consent: Patient giving signed informed consent to participate in the RC - 102 clinical study.
* Diagnosis: Patients with cancer at any stage.
* Systemic Treatment
* Remote Monitoring Eligibility: Access to a smartphone
* Language: Ability to understand and communicate in the language(s) in which the trial is conducted.

Exclusion Criteria

* Age: Patients under 18 years of age.
* Life Expectancy: Patients with a life expectancy of less than 6 months as estimated by the treating physician.
* Concurrent remote monitoring
* HSCT or CAR-T Therapy
* Cognitive Impairment
* Pregnancy or breastfeeding
* Subject under administrative or judicial control
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

UNICANCER

OTHER

Sponsor Role collaborator

Sanoia

OTHER

Sponsor Role collaborator

Resilience

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Florian Scotté, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Gustave Roussy, Cancer Campus, Grand Paris

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Hôpital Privé de Provence

Aix-en-Provence, , France

Site Status RECRUITING

Centre Hospitalier du Pays d'Aix - Centre Hospitalier Intercommunal Aix-Pertuis

Aix-en-Provence, , France

Site Status RECRUITING

Centre Hospitalier Henri Mondor-Aurillac

Aurillac, , France

Site Status RECRUITING

Centre Hospitalier de la Côte Basque

Bayonne, , France

Site Status RECRUITING

Centre Hospitalier Universitaire de Caen Normandie

Caen, , France

Site Status RECRUITING

Centre Hospitalier Universitaire de Clermont-Ferrand

Clermont-Ferrand, , France

Site Status RECRUITING

Centre Hospitalier Universitaire Grenoble - Alpes

La Tronche, , France

Site Status RECRUITING

GHICL Hôpital Saint Vincent de Paul

Lille, , France

Site Status RECRUITING

Centre Hospitalier Universitaire de Lille

Lille, , France

Site Status RECRUITING

Hôpital Privé Jean Mermoz - Institut de Cancérologie

Lyon, , France

Site Status RECRUITING

AP-HM Assistance Publique - Hôpitaux de Marseille Hôpital de la Timone

Marseille, , France

Site Status RECRUITING

Centre Hospitalier Universitaire de Nantes

Nantes, , France

Site Status RECRUITING

Hôpital Privé du Confluent

Nantes, , France

Site Status RECRUITING

Centre Hospitalier Universitaire de Nice

Nice, , France

Site Status RECRUITING

Centre Hospitalier Universitaire de Nîmes

Nîmes, , France

Site Status RECRUITING

AP-HP Hôpitaux Universitaires La Pitié Salpêtrière

Paris, , France

Site Status RECRUITING

Clinique Mutualiste Bretagne Occidentale

Quimper, , France

Site Status RECRUITING

Hôpital Privé de la Loire (HPL) - Saint Etienne

Saint-Etienne, , France

Site Status RECRUITING

Clinique Mutualiste de l'Estuaire

Saint-Nazaire, , France

Site Status RECRUITING

Centre Hospitalier Universitaire Sud Réunion

Saint-Pierre, , France

Site Status RECRUITING

Centre Clinical Elsan

Soyaux, , France

Site Status RECRUITING

Centre Hospitalier Intercommunal Toulon - La Seyne sur Mer

Toulon, , France

Site Status RECRUITING

Clinique Pasteur

Toulouse, , France

Site Status RECRUITING

Centre de Cancérologie Les Dentellières

Valenciennes, , France

Site Status RECRUITING

Clinique Teissier

Valenciennes, , France

Site Status RECRUITING

Gustave Roussy

Villejuif, , France

Site Status RECRUITING

Universitätsklinikum Schleswig-Holstein (UKSH), Campus Kiel

Kiel, , Germany

Site Status RECRUITING

Universitätsklinikum Schleswig-Holstein (UKSH), Campus Lübeck

Lübeck, , Germany

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

France Germany

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Resilience

Role: CONTACT

+33 805 69 65 61

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Salima DELLYS

Role: primary

+33.(0)4.84.49.60.43

Nabila Akkache

Role: primary

+33.(0)4.42.33.50.46

Manon MONCET

Role: primary

+33 (0)4 71 46 56 00

Emmanuelle Vignes

Role: primary

+33.(0)5.59.44.37.62

Justine Lecache

Role: primary

+33.(0)2.31.06.20.10

Céline Bonhomme

Role: primary

+33.(0)4.73.75.00.74

Amandine Ramond

Role: primary

+33.(0)4.76.76.57.55

Catherine CUNISSE

Role: primary

+33.(0)3.20.87.45.32

Jeremy DRUGEON

Role: primary

+33.(0)3.20.44.54.61

Gaëlle Le Guludec

Role: primary

+33 (0)4 37 53 87 26

Nathalie Moureau

Role: primary

+33 (0)4 91 38 73 77

Celine LEREBOURG

Role: primary

+33.(0)2.40.16.59.30

Emma CADET

Role: primary

+33 (0) 02 28 25 56 87

Enora Valle

Role: primary

+33 (0)4 92 03 82 80

Shanice Roriz

Role: primary

+33 (0)4 66 68 33 01

Direction de la Recherche Clinique et de l'Innovation

Role: primary

+33 (0)1 42 16 03 81

Karine Mas

Role: primary

+33 (0)2 57 23 05 68

Sandy MESSAOUDENE

Role: primary

+33 (0)4 77 42 29 51

Enora Valle

Role: primary

+33.(0)2.72.27.53.34

Sara MIKOLASEK

Role: primary

+262 (0)2 62 35 90 00

Corine Bustreau

Role: primary

+33 (0)5 45 69 68 32

Charline Genin

Role: primary

+33.(0)4.94.14.52.90

Sophie Bringer

Role: primary

+33.(0)5.67.20.44.01

Stéphanie Vermoesen

Role: primary

+33.(0)3.66.22.70.54

Marielle Fery

Role: primary

+33 (0)3 27 14 24 34

Sabrina Ikene

Role: primary

+33.(0)1.42.11.40.53

Emilia Prieß

Role: primary

+49 (0) 451 500 -44355

Emilia Prieß

Role: primary

+49 (0) 451 500 -44355

Related Links

Access external resources that provide additional context or updates about the study.

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

2024-A01584-43 (ID RCB)

Identifier Type: OTHER

Identifier Source: secondary_id

N° Eudamed: CIV-25-01-050834

Identifier Type: OTHER

Identifier Source: secondary_id

RC-102

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Supportive Oncology Care at Home Post-Discharge
NCT04637035 ACTIVE_NOT_RECRUITING NA