Implementing REmote SymPtom mOnitoring and maNagement (RESPONd)
NCT ID: NCT07024329
Last Updated: 2025-06-17
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
1055 participants
INTERVENTIONAL
2025-05-16
2027-03-31
Brief Summary
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The main question it aims to answer is:
• What impact does implementing digitally enabled remote symptom monitoring and management (RESPONd) between ambulatory oncology visits have on patient outcomes and system efficiencies?
Participants will:
* Report their symptoms and concerns from home by completing the electronic symptom monitoring questionnaire.
* Discuss their symptoms and concerns with a study nurse.
* Provide feedback about their experience at important timepoints during the study.
* Participate as usual in ambulatory clinic appointments.
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Detailed Description
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In recent years, cancer care has increasingly shifted from acute to ambulatory settings as a strategy to manage healthcare costs. While some emergency department (ED) visits are unavoidable due to the complexity of cancer-related issues, many could be prevented through timely symptom management and coordinated care in ambulatory oncology. The integration of Patient Reported Outcomes (PROs) into routine cancer care has been shown to reduce ED visits, enhance quality of life, and improve overall survival.
Within Cancer Care Alberta, PROs are routinely collected during clinic visits and electronically, using a standardized questionnaire that assesses common symptoms and supportive care needs experienced by cancer patients. Despite this, the use of electronic PROs data for real-time symptom management remains inconsistent, and there is currently no established workflow in Alberta for remote symptom monitoring. As a result, healthcare providers often lack advance insight into patients' symptoms prior to appointments.
Study Design:
The study is a stepped-wedge effectiveness-implementation type 1 hybrid design. RESPONd will be implemented over 1.5 years in six clinics, spanning tertiary, regional, and community cancer centres. Study nurses will monitor electronic PROs questionnaires completed between clinic visits and contact patients to provide personalized support. Collected electronic PROs information will also be utilized during weekly triage discussions in each clinic, where the route of care will be tailored for patients based on their symptom complexity. Participant quality of life will be measured at baseline, 3, and 6 months. Health care utilization compared to non-RESPONd patients will be evaluated. The implementation of this study will be evaluated using the RE-AIM framework, utilizing all constructs.
Potential impact on practice:
The study will explore a person-centered, proactive approach to remote symptom management and the effects on patient experience, outcomes, and clinical teams. RESPONd represents an innovative opportunity to shift the model of care in oncology clinics to optimize efficiency and utilization of limited clinic resources and create a responsive care team that is ready and able to provide personalized symptom management and supportive care within the cancer journey.
Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
SUPPORTIVE_CARE
NONE
Study Groups
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RESPONd
Participants will be recruited and supported to complete electronic PROs questionnaires. Study nurses will monitor the electronic PROs completed between clinic visits and contact patients to provide personalized support.
Remote Symptom Monitoring and Management
A study nurse will digitally monitor symptom complexity and provide symptom management between clinic visits. This will increase the frequency of collection and use of electronic PROs to provide responsive symptom management. Electronic PROs are collected digitally, and a complexity algorithm is used to flag patients with high symptom complexity. This will allow the study nurse to proactively manage symptoms in a timelier way.
Clinic Team Huddle
Support will be provided to clinic teams to implement a team huddle (team planning session) one week prior to clinics, to assess how additional electronic PROs data for patients participating in RESPONd impacts their ability to identify stable patients with low symptom complexity who could receive virtual care or Registered Nurse (RN) led clinic care.
Non-RESPONd
Usual care.
No interventions assigned to this group
Interventions
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Remote Symptom Monitoring and Management
A study nurse will digitally monitor symptom complexity and provide symptom management between clinic visits. This will increase the frequency of collection and use of electronic PROs to provide responsive symptom management. Electronic PROs are collected digitally, and a complexity algorithm is used to flag patients with high symptom complexity. This will allow the study nurse to proactively manage symptoms in a timelier way.
Clinic Team Huddle
Support will be provided to clinic teams to implement a team huddle (team planning session) one week prior to clinics, to assess how additional electronic PROs data for patients participating in RESPONd impacts their ability to identify stable patients with low symptom complexity who could receive virtual care or Registered Nurse (RN) led clinic care.
Eligibility Criteria
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Inclusion Criteria
* Have cancer
* Receiving care in one of the participating clinics.
* Able to sign up for MyAHS Connect and consent.
* Have access to a digital device at home
* Able to complete their electronic PROs questionnaire without support from the clinic team on a weekly (patients on active treatment) or monthly (patients on follow-up) basis, for the duration of the intervention or until they are discharged from the clinic.
* Regular access to a telephone in order for the study nurse to call patients to provide symptom management support.
Exclusion Criteria
* Patients not residing in Alberta, as government-issued ID is required to register for MyAHS Connect.
* Patients who do not have regular access to a telephone, as the study nurse needs to be able to call patients to provide symptom management support.
* Patients who do not speak English, or who do not have an English-speaking friend, family member, or caregiver to assist them, as the electronic PROs questionnaire is only available in English at this time.
18 Years
ALL
No
Sponsors
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Alberta Health services
OTHER
Alberta Innovates Health Solutions
OTHER
University of Calgary
OTHER
Responsible Party
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Linda Watson
Executive Director, Supportive Care Services and Patient Experience, Cancer Care Alberta, Alberta Health Services
Principal Investigators
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Linda Watson, RN, PhD
Role: PRINCIPAL_INVESTIGATOR
Cancer Care Alberta, Alberta Health Services
Marni Armstrong, PhD
Role: STUDY_DIRECTOR
Cancer Care Alberta, Alberta Health Services
Locations
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Arthur J. E. Child Comprehensive Cancer Centre
Calgary, Alberta, Canada
Cross Cancer Institute
Edmonton, Alberta, Canada
High River Community Cancer Centre
High River, Alberta, Canada
Central Alberta Cancer Centre
Red Deer, Alberta, Canada
Countries
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Central Contacts
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Facility Contacts
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References
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Watson L, Qi S, Link C, DeIure A, Afzal A, Barbera L. Patient-Reported Symptom Complexity and Acute Care Utilization Among Patients With Cancer: A Population-Based Study Using a Novel Symptom Complexity Algorithm and Observational Data. J Natl Compr Canc Netw. 2023 Feb;21(2):173-180. doi: 10.6004/jnccn.2022.7087.
Other Identifiers
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HREBA.CC-24-0138
Identifier Type: -
Identifier Source: org_study_id
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