Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
30 participants
OBSERVATIONAL
2024-01-16
2024-07-05
Brief Summary
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Detailed Description
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Spirometry, nitrogen wash-out, and MIP and MEP measurements are comprehensive assessments, while optoelectronic plethysmography allows restriction location through accurate measurement of thoracoabdominal volumes.
The results of the study could provide useful information about the calculation of the volumes enclosed by the grid of markers (in particular, the volume of the rib cage, which reflects the action of the intercostal muscles, the volume of the abdomen, which reflects the action of the diaphragm in the inspiratory phase and of the abdominal muscles during exhalation and their sum, which represents the total variation of the thoraco-abdominal wall. All these finds could be useful for respiratory rehabilitation protocols for obese PWS patients.
Conditions
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Study Design
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COHORT
CROSS_SECTIONAL
Study Groups
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Patients with Prader Will syndrome and BMI > 30 kg/m2
Spirometry and optoelectronic plethysmography
Spirometry for respiratory function and optoelectronic plethysmography for respiratory pattern during wakefulness
Control subjects with BMI < 25 kg/m2
Spirometry and optoelectronic plethysmography
Spirometry for respiratory function and optoelectronic plethysmography for respiratory pattern during wakefulness
Interventions
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Spirometry and optoelectronic plethysmography
Spirometry for respiratory function and optoelectronic plethysmography for respiratory pattern during wakefulness
Eligibility Criteria
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Inclusion Criteria
* Prader Willi Syndrome
* Body Mass Index \> 30 kg/m2
* Age 20-50 years
* Body Mass Index \< 25 kg/m2
Exclusion Criteria
Control subjects
* Lack of signed consent form
20 Years
50 Years
ALL
Yes
Sponsors
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Istituto Auxologico Italiano
OTHER
Responsible Party
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Locations
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Istituto Auxologico Italiano IRCCS, Site Piancavallo
Oggebbio, Verbania, Italy
Countries
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Other Identifiers
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01C318
Identifier Type: -
Identifier Source: org_study_id
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