Volontary Inspiratory Muscles Measures Compared With Phrenic Nerves Magnetic Stimulations Measures

NCT ID: NCT02078050

Last Updated: 2017-01-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

54 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-11-30

Study Completion Date

2015-05-31

Brief Summary

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Respiratory failure is the main death cause in neuromuscular diseases. Non-invasive and volitional measures of inspiratory muscles strength include the nasal pressure with an occluded nostril (Psnip) and the maximal inspiratory pressure (PImax). Unfortunately, volitional maneuvers depend of patient effort. The aim of this research is to validate a non-invasive and non-volitional technique to evaluate diaphragm strength at neuromuscular diseases patients. The methodology consists to add to PImax and Psnip measures 5 phrenic nerves magnetical stimulation maneuvers (Pstim).Stimulations will be realize at 3 inspiratory pression levels (0, -1 cm H2O and -5 cm H2O).

Detailed Description

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Conditions

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Neuromuscular Diseases Respiratory Failure

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Blinding Strategy

NONE

Study Groups

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Phrenic nerves magnetic stimulations

Group Type OTHER

Phrenic nerves magnetic stimulations

Intervention Type OTHER

Interventions

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Phrenic nerves magnetic stimulations

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* 18 years old and more men or women
* neuromuscular diseases
* Pimax and Snip evaluation Indication

Exclusion Criteria

* pregnant women
* Usual contre-indications for nuclear magnetic resonance
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre d'Investigation Clinique et Technologique 805

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Hopital R. Poincaré

Garches, , France

Site Status

Countries

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France

Other Identifiers

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2013-A00638-37

Identifier Type: -

Identifier Source: org_study_id

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