Movement Dynamics of Knee Osteoarthritis and Total Knee Replacement

NCT ID: NCT06829433

Last Updated: 2025-02-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

36 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-05-07

Study Completion Date

2026-09-30

Brief Summary

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This research aims to explore differences in walking and functional movement mechanics, exercise response, and physical activity between people with osteoarthritis (OA), those who have undergone total joint replacement, and healthy individuals.

Detailed Description

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People living with OA tend to be less physically active than those without the disease, which is often due to pain, stiffness and joint instability. This reduction in physical activity can lead to additional health problems down the line. When the disease becomes severe, joint replacement surgeries are sometimes performed to relieve pain and improve individuals' quality of life. However, despite reducing pain, there is little evidence to show that joint replacement surgeries encourage individuals to return to healthy physical activity levels.

Reasons for the lack of change may include a failure to address unhealthy walking and movement patterns which could still be causing pain and instability and reduced physical fitness levels.

By investigating these reasons, we hope that findings from this study will help to inform future interventions that improve clinical outcomes and quality of life for individuals with OA and post-joint replacement.

Conditions

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Knee Osteoarthritis Total Knee Replacement

Study Design

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Observational Model Type

CASE_CROSSOVER

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Total Knee Replacement

No intervention

Intervention Type OTHER

Observational cross-sectional study

Knee Osteoarthritis

No intervention

Intervention Type OTHER

Observational cross-sectional study

Asymptomatic Controls

No intervention

Intervention Type OTHER

Observational cross-sectional study

Interventions

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No intervention

Observational cross-sectional study

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Diagnosed symptomatic bilateral or unilateral knee osteoarthritis, self-reported ability to walk without an aid for 10 minutes and to ascend and descend stairs, no neurological conditions or other musculoskeletal pathology/injury which would impact walking gait.

Exclusion Criteria

* Unable to walk at 0.8 m/s, exclusion based on IMO screening, non-English speaking, lacking ability to consent.
Minimum Eligible Age

40 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Portsmouth

OTHER

Sponsor Role lead

Responsible Party

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Josie Morris

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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School of Psychology, Health and Sport Sciences, University of Portsmouth

Portsmouth, Hampshire, United Kingdom

Site Status RECRUITING

Countries

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United Kingdom

Central Contacts

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Josie Morris, BSc

Role: CONTACT

02392 846395

Joseph Moore, PhD

Role: CONTACT

Facility Contacts

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Josie Morris, Bsc

Role: primary

02392 846395

Other Identifiers

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SHFEC 2024-007

Identifier Type: -

Identifier Source: org_study_id

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