Optimisation of High Flow Oxygen Therapy Settings During Hypoxaemic Respiratory Distress Based on Non-contact Measurement of Lung Volumes by Depth Camera
NCT ID: NCT06819644
Last Updated: 2025-02-11
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
PHASE3
406 participants
INTERVENTIONAL
2025-02-28
2029-05-31
Brief Summary
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The main question it aims to answer is:
"The use of a technique of measurement of lung pulmonary with adjustement to the flow rate can make it possible to limite intubation in patients with HRD in intensive care?" The participants will be the patients admitted in intensive care for HRD with the need for treatment with HFO.
This participants will be randomized in :
* the arm control: treated by high flow oxygen therapy according to standard procedures.
* or in the experimental arm : treated by high flow oxygen therapy with adjustement of ventilatory parametres based on lung volume measurements, obtained by the depth camera.
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Detailed Description
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The investigators research team validated a new non-invasive, non-contact technique for measuring lung volumes using depth camera. Using a stereoscopic camera, the patient's chest and abdomen are recognized by a artificial intelligence algorithms. The structures of interest of the chest and the abdomen are the identified and the variation in depth of these points in space allows both the integration of lung volume through automatic calibration procedures, the measurement of respiratory rate and comparaison of movement symetries.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Control
The control arm will consist of patients with hypoxemic respiratory distress treated by high flow oxygen therapy according to standard procedures.
No interventions assigned to this group
interventional
The interventional arm will consist of patients with hypoxemic respiratory distress treted by high flow oxygen therapy with adjustement of ventilatory parametres based on lung volume measurements.
high flow oxygen therapy rate adjusted of lung volumes measured
Use of a technique based on non-contact measurement of lung volumes by depth camera in order to optimise the use of hihg flow oxygen therapy, with adaptation of the flow rate.
Interventions
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high flow oxygen therapy rate adjusted of lung volumes measured
Use of a technique based on non-contact measurement of lung volumes by depth camera in order to optimise the use of hihg flow oxygen therapy, with adaptation of the flow rate.
Eligibility Criteria
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Inclusion Criteria
* Respiratory rate ≥ 25 breaths per minutes
* A ratio of the partial pressure of arterial oxygen (PaO2) to the FiO2 ≤ 300 mmHg while the patient is breathing oxygen at a flow rate of 10 liters per minutes or more
* A partial pressure of arterial carbon dioxide (PaCO2) not higher than 45 mmHg
* An absence of clinical history of underlying chronic respiratory failure
Exclusion Criteria
* Pregnant or lactating woman
* Cardiogenic pulmonary edema
* Exacerbation of asthma
* Hemodynamic instability with use of vasopressor at significant dose (norepinephrine \> 0.5 mg/h)
* A Glasgow Coma Scale of 12 points of less
* Contraindications to non-invasive ventilation
* Urgent need for endotracheal intubation
* High flow oxygen therapy started within 48 hours before inclusion
* Patient under legal protection or deprived of liberty
18 Years
ALL
No
Sponsors
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University Hospital, Brest
OTHER
Responsible Party
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Locations
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AP-HP - Hôpital Louis Mourier
Colombes, , France
AP-HP - Hôpital Henri Mondor
Créteil, , France
CH Morlaix
Morlaix, , France
CHR Orléans
Orléans, , France
CH Poitiers
Poitiers, , France
CHU Rennes
Rennes, , France
CHU Tours
Tours, , France
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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2022-A01149-34
Identifier Type: OTHER
Identifier Source: secondary_id
29BRC22.0105
Identifier Type: -
Identifier Source: org_study_id
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