Based on the Data from the Zhejiang Emergency Center, Explore the Independent and Interactive Effects of the Association Between Meteorological Factors and Air Pollution and the Number of Emergency Personnel, Identify the Relevant Vulnerable Population Characteristics, Sensitive Disease Types

NCT ID: NCT06798987

Last Updated: 2025-01-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Total Enrollment

1500000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-05-01

Study Completion Date

2025-03-01

Brief Summary

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Based on the health data from Zhejiang Emergency Command Center, combined with meteorological, air pollution, land use and socio-economic data of Zhejiang Province, distributional lag nonlinear models, grouped weighted quantile and regression and Bayesian spatial models were used to explore the independent and interactive effects of the association between meteorological factors and air pollution and the number of first-aiders, to identify the related characteristics of the vulnerable populations, the types of sensitive diseases and the high-risk areas, and to elucidate the driving factors of the association between meteorological factors and air pollution and the number of first-aiders. It also clarifies the drivers of the association between meteorological factors and air pollution and the number of emergencies, so as to provide a reference for the government to take targeted measures to reduce the burden of related healthcare services.

Detailed Description

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Conditions

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Fig. Impetuous

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Interventions

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Meteorological conditions and air pollution

Climate change e.g. global surface temperature rise; extreme weather events e.g. heat waves, floods

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

-Emergency data of Zhejiang Emergency Command Center in the past 5 years

Exclusion Criteria

* Prehospital emergency information from non-Zhejiang province domains
* Emergency calls due to labor and delivery.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Li hengjie

OTHER

Sponsor Role lead

Responsible Party

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Li hengjie

Protomedicus

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Zhejiang Provincial People's Hospital

Hangzhou, , China

Site Status

Countries

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China

References

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Cui Y, Ai S, Liu Y, Qian ZM, Wang C, Sun J, Sun X, Zhang S, Syberg KM, Howard S, Qin L, Lin H. Hourly associations between ambient temperature and emergency ambulance calls in one central Chinese city: Call for an immediate emergency plan. Sci Total Environ. 2020 Apr 1;711:135046. doi: 10.1016/j.scitotenv.2019.135046. Epub 2019 Nov 3.

Reference Type BACKGROUND
PMID: 31812379 (View on PubMed)

Bobb JF, Peng RD, Bell ML, Dominici F. Heat-related mortality and adaptation to heat in the United States. Environ Health Perspect. 2014 Aug;122(8):811-6. doi: 10.1289/ehp.1307392. Epub 2014 Apr 29.

Reference Type BACKGROUND
PMID: 24780880 (View on PubMed)

Phosri A, Ueda K, Seposo X, Honda A, Takano H. Effect modification by temperature on the association between O3 and emergency ambulance dispatches in Japan: A multi-city study. Sci Total Environ. 2023 Feb 25;861:160725. doi: 10.1016/j.scitotenv.2022.160725. Epub 2022 Dec 6.

Reference Type BACKGROUND
PMID: 36493818 (View on PubMed)

Wang X, Leng M, Liu Y, Qian ZM, Zhang J, Li Z, Sun L, Qin L, Wang C, Howard SW, Vaughn MG, Yan Y, Lin H. Different sized particles associated with all-cause and cause-specific emergency ambulance calls: A multicity time-series analysis in China. Sci Total Environ. 2021 Aug 20;783:147060. doi: 10.1016/j.scitotenv.2021.147060. Epub 2021 Apr 18.

Reference Type BACKGROUND
PMID: 34088160 (View on PubMed)

Michikawa T, Sasaki J, Yamazaki S, Takami A, Asakura K, Imamura H, Ueda K, Saito S, Hoshi J, Yoshino A, Sugata S, Nitta H, Nishiwaki Y. A Case-Crossover Analysis of the Association between Exposure to Total PM2.5 and Its Chemical Components and Emergency Ambulance Dispatches in Tokyo. Environ Sci Technol. 2022 Jun 7;56(11):7319-7327. doi: 10.1021/acs.est.1c08219. Epub 2022 May 24.

Reference Type BACKGROUND
PMID: 35608996 (View on PubMed)

Dawson LP, Andrew E, Nehme Z, Bloom J, Cox S, Anderson D, Stephenson M, Lefkovits J, Taylor AJ, Kaye D, Guo Y, Smith K, Stub D. Temperature-related chest pain presentations and future projections with climate change. Sci Total Environ. 2022 Nov 20;848:157716. doi: 10.1016/j.scitotenv.2022.157716. Epub 2022 Jul 29.

Reference Type BACKGROUND
PMID: 35914598 (View on PubMed)

Sangkharat K, Mahmood MA, Thornes JE, Fisher PA, Pope FD. Impact of extreme temperatures on ambulance dispatches in London, UK. Environ Res. 2020 Mar;182:109100. doi: 10.1016/j.envres.2019.109100. Epub 2020 Jan 3.

Reference Type BACKGROUND
PMID: 31918315 (View on PubMed)

Chen R, Yin P, Wang L, Liu C, Niu Y, Wang W, Jiang Y, Liu Y, Liu J, Qi J, You J, Kan H, Zhou M. Association between ambient temperature and mortality risk and burden: time series study in 272 main Chinese cities. BMJ. 2018 Oct 31;363:k4306. doi: 10.1136/bmj.k4306.

Reference Type BACKGROUND
PMID: 30381293 (View on PubMed)

Gasparrini A, Guo Y, Hashizume M, Lavigne E, Zanobetti A, Schwartz J, Tobias A, Tong S, Rocklov J, Forsberg B, Leone M, De Sario M, Bell ML, Guo YL, Wu CF, Kan H, Yi SM, de Sousa Zanotti Stagliorio Coelho M, Saldiva PH, Honda Y, Kim H, Armstrong B. Mortality risk attributable to high and low ambient temperature: a multicountry observational study. Lancet. 2015 Jul 25;386(9991):369-75. doi: 10.1016/S0140-6736(14)62114-0. Epub 2015 May 20.

Reference Type BACKGROUND
PMID: 26003380 (View on PubMed)

Ahn J, Bae S, Chung BH, Myong JP, Park MY, Lim YH, Kang MY. Association of summer temperatures and acute kidney injury in South Korea: a case-crossover study. Int J Epidemiol. 2023 Jun 6;52(3):774-782. doi: 10.1093/ije/dyac163.

Reference Type BACKGROUND
PMID: 35950799 (View on PubMed)

Achilleos S, Al-Ozairi E, Alahmad B, Garshick E, Neophytou AM, Bouhamra W, Yassin MF, Koutrakis P. Acute effects of air pollution on mortality: A 17-year analysis in Kuwait. Environ Int. 2019 May;126:476-483. doi: 10.1016/j.envint.2019.01.072. Epub 2019 Mar 4.

Reference Type BACKGROUND
PMID: 30844583 (View on PubMed)

Fiore AM, Naik V, Spracklen DV, Steiner A, Unger N, Prather M, Bergmann D, Cameron-Smith PJ, Cionni I, Collins WJ, Dalsoren S, Eyring V, Folberth GA, Ginoux P, Horowitz LW, Josse B, Lamarque JF, MacKenzie IA, Nagashima T, O'Connor FM, Righi M, Rumbold ST, Shindell DT, Skeie RB, Sudo K, Szopa S, Takemura T, Zeng G. Global air quality and climate. Chem Soc Rev. 2012 Oct 7;41(19):6663-83. doi: 10.1039/c2cs35095e. Epub 2012 Aug 6.

Reference Type BACKGROUND
PMID: 22868337 (View on PubMed)

Chen K, Wolf K, Breitner S, Gasparrini A, Stafoggia M, Samoli E, Andersen ZJ, Bero-Bedada G, Bellander T, Hennig F, Jacquemin B, Pekkanen J, Hampel R, Cyrys J, Peters A, Schneider A; UF&HEALTH Study Group. Two-way effect modifications of air pollution and air temperature on total natural and cardiovascular mortality in eight European urban areas. Environ Int. 2018 Jul;116:186-196. doi: 10.1016/j.envint.2018.04.021. Epub 2018 Apr 22.

Reference Type BACKGROUND
PMID: 29689465 (View on PubMed)

Doherty RM, Heal MR, O'Connor FM. Climate change impacts on human health over Europe through its effect on air quality. Environ Health. 2017 Dec 5;16(Suppl 1):118. doi: 10.1186/s12940-017-0325-2.

Reference Type BACKGROUND
PMID: 29219103 (View on PubMed)

Ebi KL, Capon A, Berry P, Broderick C, de Dear R, Havenith G, Honda Y, Kovats RS, Ma W, Malik A, Morris NB, Nybo L, Seneviratne SI, Vanos J, Jay O. Hot weather and heat extremes: health risks. Lancet. 2021 Aug 21;398(10301):698-708. doi: 10.1016/S0140-6736(21)01208-3.

Reference Type BACKGROUND
PMID: 34419205 (View on PubMed)

Khoshakhlagh AH, Mohammadzadeh M, Gruszecka-Kosowska A, Oikonomou E. Burden of cardiovascular disease attributed to air pollution: a systematic review. Global Health. 2024 May 3;20(1):37. doi: 10.1186/s12992-024-01040-0.

Reference Type BACKGROUND
PMID: 38702798 (View on PubMed)

Other Identifiers

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QT202146

Identifier Type: -

Identifier Source: org_study_id

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