Monitoring of Hydration Status in Chronic Hemodialysis Patients

NCT ID: NCT06798272

Last Updated: 2025-01-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-10-10

Study Completion Date

2024-03-15

Brief Summary

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Background Maintaining fluid balance is one of major challenges of the dialysis therapy. It includes, in particular, the management of "dry body mass". We postulated that simple measurement of subscapular skinfold thickness before and after hemodialysis could help monitor hydration status in chronic dialysis patients.

Aim of the study The aim of the study was to compare the conventional methods of monitoring hydration status during hemodialysis with an assessment of skin fold thickness.

Materials and Methods 50 participants (21 F, 29 M; age 60 ±15 years) were enrolled. Directly before the hemodialysis session the following parameters were measured: body composition with bioimpedance spectroscopy, skinfold thickness in subscapular area with standardized caliper and blood tests: blood count, urea, n-terminal pro B-type natriuretic peptide (nt-proBNP) and pro-adrenomedullin (pro-ADM). The procedures were repeated at the end of three consecutive hemodialysis sessions.

Detailed Description

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Conditions

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Hemodialysis Kidney Failure Overhydration

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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changes of overhydration during hemodialysis session

Group Type EXPERIMENTAL

dialysisis with and without glucose in the dialysis

Intervention Type PROCEDURE

there were assessed three consecutive hemodialysis sessions

Interventions

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dialysisis with and without glucose in the dialysis

there were assessed three consecutive hemodialysis sessions

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* chronic hemodialysis for at least 3 months

Exclusion Criteria

* severe mental disabilities, poor compliance, any acute infection, instability of the cardiovascular hemodynamic condition
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medical University of Lodz

OTHER

Sponsor Role lead

Responsible Party

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Michal Nowicki

Professor MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Central University Hospital

Lodz, , Poland

Site Status

Countries

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Poland

Other Identifiers

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163/20

Identifier Type: -

Identifier Source: org_study_id

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