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Communication Strategies to Increase HPV Vaccination Intention

NCT ID: NCT06784960

Last Updated: 2025-03-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

3689 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-02-06

Study Completion Date

2026-03-31

Brief Summary

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This research aims to identify communication strategies to improve the uptake of vaccines using an experimental design, focusing on the Human Papillomavirus (HPV) vaccine, which is highly effective in preventing HPV-related cancers. However, low HPV vaccination rates among adults remain a significant public health challenge. Although randomized controlled trials (RCTs) have demonstrated that interventions can increase vaccine uptake in children, few RCTs have been conducted on adults. To address this gap, a multidisciplinary investigative team with expertise in communication, medicine, nursing, and behavior-change intervention research, and a history of extensive collaboration, will conduct a survey experiment on a national sample of over 3,689 adults to identify the most promising theory-based messages to strengthen HPV vaccine intentions.

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Detailed Description

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Conditions

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Papilloma Viral Infection Vaccine Hesitancy Communication

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Theory-Based Message Condition 1

Group Type EXPERIMENTAL

Messages

Intervention Type BEHAVIORAL

We will randomly assign participants in equal numbers to one of five theory-based HPV vaccine message conditions or an attention-matched control arm.

Theory-Based Message Condition 2

Group Type EXPERIMENTAL

Messages

Intervention Type BEHAVIORAL

We will randomly assign participants in equal numbers to one of five theory-based HPV vaccine message conditions or an attention-matched control arm.

Theory-Based Message Condition 3

Group Type EXPERIMENTAL

Messages

Intervention Type BEHAVIORAL

We will randomly assign participants in equal numbers to one of five theory-based HPV vaccine message conditions or an attention-matched control arm.

Theory-Based Message Condition 4

Group Type EXPERIMENTAL

Messages

Intervention Type BEHAVIORAL

We will randomly assign participants in equal numbers to one of five theory-based HPV vaccine message conditions or an attention-matched control arm.

Theory-Based Message Condition 5

Group Type EXPERIMENTAL

Messages

Intervention Type BEHAVIORAL

We will randomly assign participants in equal numbers to one of five theory-based HPV vaccine message conditions or an attention-matched control arm.

Theory-Based Message Condition 6

Group Type ACTIVE_COMPARATOR

Messages

Intervention Type BEHAVIORAL

We will randomly assign participants in equal numbers to one of five theory-based HPV vaccine message conditions or an attention-matched control arm.

Interventions

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Messages

We will randomly assign participants in equal numbers to one of five theory-based HPV vaccine message conditions or an attention-matched control arm.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* 18-45 years old

Exclusion Criteria

* Under 18 and over 45 years old
* Received HPV vaccine or unsure about receipt
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Pennsylvania

OTHER

Sponsor Role lead

Responsible Party

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Florence Momplaisir, MD

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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University of Pennsylvania

Philadelphia, Pennsylvania, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Florence Momplaisir

Role: CONTACT

[email protected]
215-746-8555

Facility Contacts

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Florence Momplaisir

Role: primary

[email protected]
215-746-8555

Other Identifiers

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856892

Identifier Type: -

Identifier Source: org_study_id

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