Culturally Targeted Health Communication and Receptivity to the Human Papillomavirus Vaccine Among Parents in Flint, MI

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

265 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-11-17

Study Completion Date

2026-06-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The goal of this clinical trial is to learn if culturally targeted messaging about the human papillomavirus (HPV) increases receptivity to the HPV vaccine among African American parents of vaccine-eligible daughters. The main question it aims to answer is:

• Does culturally targeted messaging increase African American parents' intentions to vaccinate their daughter against HPV?

Research will compare culturally targeted messaging to general, educational messaging and no messaging.

Participants will:

* View culturally targeted messages, education-only messages, or no messages about the HPV vaccine
* Report their intentions to vaccinate their daughter against HPV
* Report whether they have initiated HPV vaccination for their daughter six months later

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Text and Talk: A Multi-level Intervention to Increase Provider HPV Vaccine Recommendation Effectiveness

NCT05006833

HPV

ACTIVE_NOT_RECRUITING NA

PREVENT Pilot HPV - Related Cancers Trial

NCT06738355

HPV Vaccination Uptake Vaccination Series Completion

COMPLETED NA

An Evaluation of Tailored Messages to Address Parental Questions About HPV Vaccination

NCT03628885

Human Papilloma Virus Vaccines Attitude to Health

COMPLETED NA

Tailoring of Vaccine-Focused Messages: Disease Salience

NCT03002324

Human Papillomavirus

COMPLETED NA

Message Framing in HPV Vaccination Decision

NCT07068802

HPV Vaccination Intention Among Male College Students

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Cervical cancer incidence and mortality are higher for African American women than for White women. The human papillomavirus (HPV) vaccine is the most effective strategy for reducing risk for cervical cancer. However, African American girls are less likely to have completed the HPV vaccine series than White girls. The present research will evaluate a culturally targeted approach to health messaging about the HPV vaccine for parents with vaccine-eligible daughters. The central hypothesis is that African American parents will have greater receptivity to the HPV vaccine after receiving culturally targeted messaging compared to parents who receive no messaging or education-only messaging about HPV vaccination. The primary aims are: 1) evaluate effects of HPV vaccine education on White and African American parents' receptivity to the HPV vaccine, and whether culturally targeted messaging enhances HPV vaccine receptivity among African American parents, 2) compare effects of education-only versus culturally targeted messaging on activation of racism-related thinking when considering child HPV vaccination, and 3) examine the effects of racism-related medical mistrust on the effectiveness of culturally targeted messaging. General and culturally targeted messaging about the HPV vaccine were developed in collaboration with community members and a local health educator. Participants will report their intentions to vaccinate their daughter against HPV immediately after viewing health messaging, as well as initiation of the HPV vaccine series for their daughter 6-months post-messaging.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

HPV Vaccination

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

This research will use a 2 (White, African American) x 3 (No message, Education-only message, Culturally targeted message) quasi-experimental design. All participants will be randomly assigned to a no-message control group or to receive educational materials about HPV vaccination. Half of African American parents who receive educational materials will also view culturally targeted messaging about the HPV vaccine.

Primary Study Purpose

OTHER

Blinding Strategy

SINGLE

Participants

Participants will be unaware of their assignment to a general, education-only versus culturally targeted messaging condition.

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

African American Culturally Targeted Messaging

Culturally targeted messaging about the HPV vaccine for African American parents

Group Type EXPERIMENTAL

Culturally Targeted HPV Vaccine Health Messaging

Intervention Type BEHAVIORAL

Educational messaging about the HPV vaccine includes culturally targeted messaging about the HPV vaccine.

African American General, Education-Only Messaging

African American participants receive general, education-only messaging about the HPV vaccine.

Group Type ACTIVE_COMPARATOR

General HPV Vaccine Health Messaging

Intervention Type BEHAVIORAL

General, education-only messaging about the HPV vaccine does not include culturally targeted messaging.

African American No Message

African American participants receive no messaging about the HPV vaccine

Group Type NO_INTERVENTION

No interventions assigned to this group

White General, Education-Only Messaging

White participants receive general, education-only messaging about the HPV vaccine.

Group Type ACTIVE_COMPARATOR

General HPV Vaccine Health Messaging

Intervention Type BEHAVIORAL

General, education-only messaging about the HPV vaccine does not include culturally targeted messaging.

White No Message

White participants receive no messaging about the HPV vaccine

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

General HPV Vaccine Health Messaging

General, education-only messaging about the HPV vaccine does not include culturally targeted messaging.

Intervention Type BEHAVIORAL

Culturally Targeted HPV Vaccine Health Messaging

Educational messaging about the HPV vaccine includes culturally targeted messaging about the HPV vaccine.

Intervention Type BEHAVIORAL

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Identify as Black/African American or White/Caucasian
* Have at least one daughter who is between 8-17 years of age, who is not currently pregnant, and who has not received any doses of the HPV vaccine