Pilot Study of Open Label Homocysteine Management Therapy in Levodopa-treated Parkinson's Disease
NCT ID: NCT06772220
Last Updated: 2025-01-13
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
150 participants
INTERVENTIONAL
2024-03-05
2025-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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B vitamin regimen
Daily doses of 1mg folic acid, 25mg vitamin B6, and 1,000 ug vitamin B12.
Folic Acid 1 MG
Folic Acid 1mg per day
Vitamin B6 25 MG
Vitamin B6, 25mg per day
Vitamin B12
Vitamin B12, 1,000 ug per day
No vitamins
No vitamin intervention.
No interventions assigned to this group
Interventions
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Folic Acid 1 MG
Folic Acid 1mg per day
Vitamin B6 25 MG
Vitamin B6, 25mg per day
Vitamin B12
Vitamin B12, 1,000 ug per day
Eligibility Criteria
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Inclusion Criteria
2. Currently treated with levodopa at a minimum dose of 300 mg/day
3. Montreal Cognitive Assessment (MOCA) ≥15
4. Demonstrated capacity to provide informed consent.
5. 40-90 years of age
6. Estimated glomerular filtration rate ≥60
7. Absence of uncontrolled hypertension in medical history
8. Absence of insulin use
Exclusion Criteria
40 Years
90 Years
ALL
No
Sponsors
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Oregon Health and Science University
OTHER
Responsible Party
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Joseph Quinn
OHSU Parkinson Center Director
Principal Investigators
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Joseph Quinn, MD
Role: PRINCIPAL_INVESTIGATOR
Oregon Health & Science University (OHSU)
Locations
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Oregon Health & Science University (OHSU)
Portland, Oregon, United States
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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PF-CER-979199
Identifier Type: OTHER_GRANT
Identifier Source: secondary_id
IRB 25171
Identifier Type: -
Identifier Source: org_study_id
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