Analysis of Biological Progression and Regression of HELLP Syndrome in Time

NCT ID: NCT06758960

Last Updated: 2025-01-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Total Enrollment

70 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-07-01

Study Completion Date

2025-08-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Prospective observational study about progression and regression of biological parameters of HELLP syndrome

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Data collection included a comprehensive review of pathological histories, identification of complications based on clinical presentation, daily monitoring of biological parameters, documentation of transfusion events, recording of corticosteroid administration according to gestational age, and detailed reporting of extraction and analgesia techniques.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

HELLP Syndrome Preeclampsia

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Pregnant women who are admitted to the maternal ICU for a biological HELLP syndrome

Exclusion Criteria

* Patients whose biological presentation was attributable to other conditions, such as microangiopathies or leukemia.
* Patients who benefited from plasma exchange therapy
Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

CHU Mohammed VI Marrakech

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Meryem Essafti

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Meryem Essafti, Assistant Professor

Role: STUDY_DIRECTOR

CHU Mohammed VI Marrakech

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

CHU Mohammed VI of Marrakech

Marrakesh, Marrakech - Safi, Morocco

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

Morocco

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Nizar Amllah, M.D

Role: CONTACT

+212 613069684

Meryem Essafti, Assistant Professor

Role: CONTACT

+212 662393700

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Nizar Amllah, M.D

Role: primary

+212 613069684

References

Explore related publications, articles, or registry entries linked to this study.

Martin JN Jr, Blake PG, Lowry SL, Perry KG Jr, Files JC, Morrison JC. Pregnancy complicated by preeclampsia-eclampsia with the syndrome of hemolysis, elevated liver enzymes, and low platelet count: how rapid is postpartum recovery? Obstet Gynecol. 1990 Nov;76(5 Pt 1):737-41. doi: 10.1097/00006250-199011000-00001.

Reference Type BACKGROUND
PMID: 2216215 (View on PubMed)

Martin JN Jr, Blake PG, Perry KG Jr, McCaul JF, Hess LW, Martin RW. The natural history of HELLP syndrome: patterns of disease progression and regression. Am J Obstet Gynecol. 1991 Jun;164(6 Pt 1):1500-9; discussion 1509-13. doi: 10.1016/0002-9378(91)91429-z.

Reference Type BACKGROUND
PMID: 2048596 (View on PubMed)

Provided Documents

Download supplemental materials such as informed consent forms, study protocols, or participant manuals.

Document Type: Study Protocol

View Document

Document Type: Informed Consent Form

View Document

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

67/2024

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.