Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
80 participants
INTERVENTIONAL
2025-02-01
2026-03-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Amo group
amobarbital 1mg/kg is given prior to cardiopulmonary bypass
Amobarbital
Amobarbital 1mg/kg is given prior to cardiopulmonary bypass
Mida group
midazolam 0.1mg/kg is given prior to cardiopulmonary bypass
Midazolam
midazolam 0.1mg/kg is given prior to cardiopulmonary bypass
Interventions
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Amobarbital
Amobarbital 1mg/kg is given prior to cardiopulmonary bypass
Midazolam
midazolam 0.1mg/kg is given prior to cardiopulmonary bypass
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* ASA II-III;
* surgical duration is 3-6 hours;
* Sign the informed consent form
Exclusion Criteria
* Individuals with a history or potential history of drug abuse or alcohol dependence;
* Preoperative use of sedatives or analgesics;
* Individuals with severe liver and kidney dysfunction;
* Individuals who are allergic or potentially allergic to barbiturates;
* Patients with coagulation dysfunction, endocrine disorders, or other conditions that affect hemodynamic status;
* Participated in other clinical studies in the past 3 months;
* The researchers believe that participants who are not suitable to participate in this study.
18 Years
65 Years
ALL
No
Sponsors
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Tongji Hospital
OTHER
Responsible Party
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aijun xu
Doctor
Principal Investigators
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Aihua Du, Dr
Role: STUDY_CHAIR
Tongji Hospital
Locations
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Tongji hospital
Wuhan, Hubei, China
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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AMOC
Identifier Type: -
Identifier Source: org_study_id
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