Weight Reduction With the Low-Insulin-Method - Self Monitoring of Breath Acetone

NCT ID: NCT06745362

Last Updated: 2025-06-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

42 participants

Study Classification

INTERVENTIONAL

Study Start Date

2026-01-01

Study Completion Date

2027-12-31

Brief Summary

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The goal of this clinical trial is to learn if lifestyle intervention with information about ketosis state supports weight reduction in overweight adults.

Researchers will compare an App-based lifestyle intervention with self-monitoring of breath acetone vs. lifestyle intervention alone.

Participants will:

Get a lifestyle intervention via the LIM-App for 12 months. Report body weight.

Detailed Description

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Background: Overweight and obesity are an increasing problem. Therefore, the Low-Insulin-Method was developed to support overweight and obese people in weight loss.

Method: In a randomized controlled clinical trial, the effect of the lifestyle intervention program 'Low-Insulin-Method', delivered by the Low-Insulin-App including low-carb diet, physical activity, self monitoring of weight, and self-monitoring of breath acetone (SMBA) is examined compared to a control group without information about ketosis level. Weight change will be compared after 3 and 12 months.

Objective: The aim is to develop a training and counseling program for overweight or obese individuals with diabetes risk or type 2 diabetes, which can be used both for primary and for tertiary prevention of overweight-related diseases.

Conditions

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Overweight and Obese Volunteers

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

TRIPLE

Caregivers Investigators Outcome Assessors

Study Groups

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Intervention group

lifestyle intervention including information about ketosis level

Group Type EXPERIMENTAL

self-monitoring of breath acetone

Intervention Type OTHER

Participants perform self-monitoring of braeth acetone in order to get information about their ketosis state.

lifestyle-intervention via LIM-App

Intervention Type OTHER

Participants are offered a lifestyle intervention via LIM-App.

control group

lifestyle intervention without information about ketosis level

Group Type ACTIVE_COMPARATOR

lifestyle-intervention via LIM-App

Intervention Type OTHER

Participants are offered a lifestyle intervention via LIM-App.

Interventions

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self-monitoring of breath acetone

Participants perform self-monitoring of braeth acetone in order to get information about their ketosis state.

Intervention Type OTHER

lifestyle-intervention via LIM-App

Participants are offered a lifestyle intervention via LIM-App.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Body Mass Index \> 25kg/m2

Exclusion Criteria

\-
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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West German Center of Diabetes and Health

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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West German Center of Diabetes and Health

Düsseldorf, , Germany

Site Status

Countries

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Germany

Central Contacts

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Stephan Martin

Role: CONTACT

049-2115660360 ext. 70

Facility Contacts

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Stephan Martin

Role: primary

049-2115660360 ext. 70

Other Identifiers

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20241217

Identifier Type: -

Identifier Source: org_study_id

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