Medically Intensive Nutrition Therapy Program for Obesity and Diabetes in a Low-income Population

NCT ID: NCT05799222

Last Updated: 2025-12-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

20 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-03-28

Study Completion Date

2026-11-10

Brief Summary

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This study is being done to better understand whether meal replacements can be an effective tool for weight loss and treatment of elevated blood sugars in people with obesity/overweight and diabetes/pre-diabetes who have a low income.

Detailed Description

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The Medically Intensive Nutritional Therapy (MINT) program at Massachusetts General Hospital (MGH) Weight Center is a low-calorie nutrition plan that may offer a solution for those who have difficulty implementing a low-calorie dietary plan on their own. This study examines the effects of MINT on weight loss and blood sugar control specifically in a low-income population and explores potential reasons for discontinuing the program.

Conditions

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Overweight PreDiabetes Diabetes Type 2 Obesity

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Adults with overweight/obesity and pre-diabetes/diabetes and low income

Adults with overweight or obesity and pre-diabetes or type 2 diabetes who earn a low income.

Bariatrix Meal Replacement Products

Intervention Type DIETARY_SUPPLEMENT

Meal replacement products offered through the Massachusetts General Hospital Weight Center.

Interventions

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Bariatrix Meal Replacement Products

Meal replacement products offered through the Massachusetts General Hospital Weight Center.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Age 18-65
* Body mass index (BMI) greater than or equal to 27 kg/m\^2
* HgA1C greater than or equal to 5.7 percent or fasting glucose greater than or equal to 100mg/dL within the previous 6 months
* Low-income as defined by having a family income at or below 400 percent of the federal poverty level guidelines for 2022

Exclusion Criteria

* Current use of antihyperglycemic agents (other than metformin) or approved anti- obesity medications or plans to start such regimens over the 3 months post-study enrollment
* HbA1c greater than or equal to 10 percent
* Plans to pursue bariatric surgery over the 6 months post-study enrollment
* Weight loss of greater than 5 kg within the previous 3 months
* Current active eating disorder, with the exception of binge eating disorder
* Severe active psychiatric disease or significant cognitive impairment deemed by investigator likely to impede adherence to piloted intervention
* Active illicit substance abuse
* Pregnant, breastfeeding, or considering pregnancy within the next 6 months
* Current participation in another clinical research trial deemed by investigator to conflict with current study
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Massachusetts General Hospital

OTHER

Sponsor Role lead

Responsible Party

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Chika V. Anekwe, MD, MPH

Instructor in Medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Chika V Anekwe, MD

Role: PRINCIPAL_INVESTIGATOR

Massachusetts General Hospital

Locations

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Massachusetts General Hospital

Boston, Massachusetts, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Chika V Anekwe, MD

Role: CONTACT

Phone: 617-726-4400

Email: [email protected]

Facility Contacts

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Chika V Anekwe, MD

Role: primary

Other Identifiers

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2022P001451

Identifier Type: -

Identifier Source: org_study_id