Erector Spinae Plane Block Versus Retrolaminar Block for Analgesia in Percutaneous Nephrolithotomy

NCT ID: NCT06710444

Last Updated: 2025-05-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-12-01

Study Completion Date

2025-04-01

Brief Summary

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The study will investigate the effects of ultrasound-guided ESPB and RLB on intraoperative and postoperative analgesia in patients undergoing PCNL to identify a safe and effective regional block method for postoperative analgesia

Detailed Description

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All the patients will be blinded to the intervention received in this study. All patients will receive standard general anesthesia technique with endotracheal intubation and muscle paralysis. Postoperatively, all patients will receive analgesia in the form of non-steroidal anti-inflammatory drugs and paracetamol. In case the VAS scores exceeded 4 in any group, the patients will receive rescue analgesia with 25 mg IV meperidine. In both groups, the ESPB and RLB will be performed after induction of general anesthesia using portable ultrasound device.

Conditions

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Postoperative Analgesia Pain Management PCNL Regional Anesthesia Block

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Caregivers Outcome Assessors

Study Groups

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Group I

This group will receive ultrasound-guided erector spinae plane block

Group Type ACTIVE_COMPARATOR

ultrasound-guided erector spinae plane block

Intervention Type PROCEDURE

ESPB

Group II

This group will receive ultrasound-guided Retrolaminar plane block

Group Type EXPERIMENTAL

ultrasound-guided retrolaminar plane block

Intervention Type PROCEDURE

RLB

Interventions

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ultrasound-guided erector spinae plane block

ESPB

Intervention Type PROCEDURE

ultrasound-guided retrolaminar plane block

RLB

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

\- Patients scheduled for PCNL

Exclusion Criteria

* daily consumption of analgesics
* allergy to local anesthetics
* liver dysfunction
* infection or previous surgery in the vertebral region.
* patient refusal
* pregnancy
Minimum Eligible Age

21 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Alexandria University

OTHER

Sponsor Role lead

Responsible Party

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Ahmed Shehab, MD

Lecturer in Anaesthesia and Surgical ICU department

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Ahmed S. Shehab, MD

Role: PRINCIPAL_INVESTIGATOR

Alexandria University

Locations

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Ahmed S.Shehab

Alexandria, , Egypt

Site Status

Countries

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Egypt

References

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Sotome S, Sawada A, Wada A, Shima H, Kutomi G, Yamakage M. Erector spinae plane block versus retrolaminar block for postoperative analgesia after breast surgery: a randomized controlled trial. J Anesth. 2021 Feb;35(1):27-34. doi: 10.1007/s00540-020-02855-y. Epub 2020 Sep 11.

Reference Type BACKGROUND
PMID: 32915300 (View on PubMed)

Other Identifiers

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0306627

Identifier Type: -

Identifier Source: org_study_id

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