Evaluation of Fractalkine and Its Receptor in Peri-implantitis

NCT ID: NCT06685523

Last Updated: 2024-11-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-11-08

Study Completion Date

2025-05-15

Brief Summary

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In this study, mechanical debridement group, Er:YAG laser group and diode laser group will be compared in terms of reducing peri-implant sulcus depth in the treatment of peri-implantitis.

Detailed Description

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Conditions

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Peri-implantitis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Four group:

* Peri-implant healty
* Mechanical curette
* Er:YAG laser
* Diyot laser
Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Investigators Outcome Assessors

Study Groups

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Group healty

Group Type NO_INTERVENTION

No interventions assigned to this group

Mechanical debridement group

Group Type EXPERIMENTAL

Subgingival debridement

Intervention Type PROCEDURE

To be applied 1 times (0. days)

Er:YAG laser applied group

Group Type EXPERIMENTAL

Er:YAG laser decontamination

Intervention Type PROCEDURE

To be applied 3 times

Diyot laser applied group

Group Type EXPERIMENTAL

Diyot laser decontamination

Intervention Type PROCEDURE

To be applied 3 times

Interventions

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Subgingival debridement

To be applied 1 times (0. days)

Intervention Type PROCEDURE

Er:YAG laser decontamination

To be applied 3 times

Intervention Type PROCEDURE

Diyot laser decontamination

To be applied 3 times

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Probing depth of 4-6 mm, bone loss of at least 2 mm on X-ray and presence of inflammatory symptoms in soft tissue
* No systemic disease that may affect the outcome of the treatment
* Patients with healthy periodontium or patients with completed periodontal treatment
* Individuals at least 6 months after prosthesis loading on the implant
* Individuals who do not require further surgery for the treatment of peri-implantitis
* Implants with at least 2 mm keratised gingiva
* Individuals aged 40-60 years

Exclusion Criteria

* Individuals undergoing radiation therapy
* Individuals who smoke and drink alcohol
* Individuals in pregnancy or lactation
* Individuals who have received antibiotic treatment in the last three months
* Individuals with parafunctional habits
Minimum Eligible Age

40 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Kubilay BARIŞ

OTHER

Sponsor Role lead

Responsible Party

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Kubilay BARIŞ

Assistant Professor

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Kırıkkale University, Faculty of Dentistry, Department of Periodontology

Kırıkkale, , Turkey (Türkiye)

Site Status RECRUITING

Countries

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Turkey (Türkiye)

Central Contacts

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Kubilay Barış, Dr.

Role: CONTACT

+90-0553-973-64-77

Facility Contacts

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Musa Bulut, Staff

Role: primary

+90-552-784-71-00

Other Identifiers

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KU-DHF-KB-01

Identifier Type: -

Identifier Source: org_study_id

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