Treatment of Peri-implant Mucositis and Supportive Peri-implant Therapy
NCT ID: NCT06137846
Last Updated: 2025-08-24
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
52 participants
INTERVENTIONAL
2023-10-31
2025-06-20
Brief Summary
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Detailed Description
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Up to 60 participants with dental implants will be recruited from patients seeking and/or receiving dental care at the University of Michigan Graduate Periodontics department, until 34 peri-mucositis participants and 17 healthy participants are achieved.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Peri-mucositis
Dental implant has peri-implant mucositis
Air-Polish
Dental implant will be cleaned with an airpolishing device
Ultrasonic
Dental implant will be cleaned with an ultrasonic device with a plastic tip
Healthy
Dental implant does not have peri-implant mucositis
Air-Polish
Dental implant will be cleaned with an airpolishing device
Interventions
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Air-Polish
Dental implant will be cleaned with an airpolishing device
Ultrasonic
Dental implant will be cleaned with an ultrasonic device with a plastic tip
Eligibility Criteria
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Inclusion Criteria
2. Healthy systemic conditions (American Society of Anesthesiologists classification (ASA) I or II: systemically healthy or suffer from mild to moderate, but well controlled systemic diseases).
3. Must have at least one osseointegrated dental implant with the following conditions (Berglundh et al. 2018a).
* At least 12 months since the prosthesis was placed.
* Absence of bone loss beyond crestal bone level changes from initial bone remodeling.
* For implant mucositis subjects: Presence of bleeding and/or suppuration on gentle probing around implant at least 2 sites. Visual inspection demonstrating the presence of peri-implant signs of inflammation.
* For healthy implant subjects: Absence of bleeding and/or suppuration on gentle probing around implant.
4. Have a current (less than 6 months old) x-ray of the affected site
5. All participants must be enrolled in a 3 to 6 months maintenance recall program including teeth/implants prophylaxis and supportive periodontal therapy.
Exclusion Criteria
2. Uncontrolled systemic disease or condition known to alter bone metabolism. (e.g. osteoporosis, osteopenia, hyperparathyroidism, Paget's disease)
3. Current smokers or vapers.
4. Pregnancy or could be pregnant (self-reported), or plan to be pregnant in the next 6 months.
5. Long-term (3 months) intake of anti-inflammatory medications (e.g. non-steroidal anti-inflammatory drugs (NSAIDs)) known to affect periodontal status within one month previous to participation in the study.
6. Taking corticosteroids.
7. Long-term antibiotic use (\> one weeks) within three months previous to participation in the study.
8. No history of supragingival scaling or non-surgical therapy at the affected implant site in the last 1 month.
9. Taking anticoagulant medications.
10. Subjects who require prophylactic antibiotics.
18 Years
85 Years
ALL
Yes
Sponsors
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University of Michigan
OTHER
Responsible Party
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Hom-Lay Wang, DDS, MSD, Ph D
Collegiate Professor of Periodontics and Professor of Dentistry
Principal Investigators
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Hom-Lay Wang, DDS MSD PhD
Role: PRINCIPAL_INVESTIGATOR
Department of Periodontics and Oral Medicine University of Michigan
Locations
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University of Michigan School of Dentistry
Ann Arbor, Michigan, United States
Countries
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Other Identifiers
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HUM00164918
Identifier Type: -
Identifier Source: org_study_id
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