Efficacy of Diode Laser in Peri-implantitis

NCT ID: NCT02362854

Last Updated: 2015-02-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-02-28

Study Completion Date

2014-07-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The aim of this study was to compare the efficacy of a diode laser (DL) as an adjunct to conventional scaling in the treatment of mild-to-moderate peri-implantitis. A prospective clinical, radiographic and microbiologic split-mouth study was conducted to test the following null hypothesis; adjunct application of a diode laser, in the conventional treatment of peri-implantitis, are not associated with a statistically significant difference regarding the microbial counts, marginal bone loss and peri-implant parameters.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Efficacy of a diode laser (DL) in peri-implantitis was investigated. 48 implants diagnosed with peri-implantitis were included. In addition to the conventional scaling and debridement, random 24 implants were lased by a DL. Periodontal indexes, microbiologic specimens and radiographs were used for assessment. Baseline parameters were similar between groups. After six months laser group revealed higher MBL than the control group. Microbiota of the implants were found unchanged after one month. DL appears to have no additional positive influence on the peri-implantitis treatment.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Implant Peri-Implantitis Alveolar Bone Loss Complications

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Conventional peri-implantitis treatment

Peri-implantitis treatment according to the Cumulative interceptive supportive (CIST) therapy.

Group Type ACTIVE_COMPARATOR

Conventional peri-implantitis treatment

Intervention Type PROCEDURE

Elimination of the bacterial plaque. Establishing optimal healing conditions. Detoxification of the affected environment.

DL application in peri-implantitis

Adjunct Diode Laser application.

Group Type EXPERIMENTAL

DL application in peri-implantitis

Intervention Type DEVICE

Diode laser application in the diseased implants.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Conventional peri-implantitis treatment

Elimination of the bacterial plaque. Establishing optimal healing conditions. Detoxification of the affected environment.

Intervention Type PROCEDURE

DL application in peri-implantitis

Diode laser application in the diseased implants.

Intervention Type DEVICE

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

CIST treatment protocol

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* 18 years and older
* No local and systemic health problems prohibit the study interventions
* Bi-lateral implants with peri-implantitis diagnosis

Exclusion Criteria

* Local and systemic health problems prohibiting the study interventions
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Istanbul University Research Fund

UNKNOWN

Sponsor Role collaborator

Istanbul University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Volkan Arisan

Assoc.Prof.Dr

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Volkan Arısan, Ass.Prof.Dr.

Role: STUDY_CHAIR

Istanbul University, Faculty of Dentistry

Cuneyt Karabuda, Prof.Dr.

Role: STUDY_DIRECTOR

Istanbul University, Faculty of Dentistry

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Department of Oral Implantology, Faculty of Dentistry, Istanbul University

Istanbul, Capa, Turkey (Türkiye)

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Turkey (Türkiye)

Related Links

Access external resources that provide additional context or updates about the study.

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

IstanbulU

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.